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Self-heated traditional Chinese medicine (TCM) emplastrum for improving sleep quality

A sleep-improving, self-heating technology that is applied to heating appliances for treatment, drug combinations, and pharmaceutical formulas, etc.

Active Publication Date: 2013-04-03
GUANGZHOU NEW DESIGN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the medicine disclosed in the above patent application has the function of regulating viscera, it can achieve the functions of nourishing qi and blood, relaxing the brain, balancing yin and yang, and improving sleep. However, it is absorbed through the skin by bathing the feet. or use

Method used

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  • Self-heated traditional Chinese medicine (TCM) emplastrum for improving sleep quality
  • Self-heated traditional Chinese medicine (TCM) emplastrum for improving sleep quality
  • Self-heated traditional Chinese medicine (TCM) emplastrum for improving sleep quality

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] 1. Preparation of plaster:

[0062] Prescription of raw materials: 8g rose sesame oil, 120g bark of Albizia Julibrissin, 120g of Caulis japonica, 80g of cinnamon, 40g of schisandra, 32g of calamus.

[0063] Matrix formula: 31g gelatin, 12g sodium carboxymethylcellulose, 8g polyvinyl alcohol, 88g pressure-sensitive adhesive, 24g carbomer, 250g glycerol, 250g propylene glycol, 5g kaolin, 5g zinc oxide, 9g citric acid, citric acid Sodium 33g, water 285g.

[0064] Preparation of the water extract: decoct Albizia Julibrissin, vine, cinnamon, schisandra and calamus with water twice, add 6 times the amount of water for the first time, add 6 times the amount of water for the second time, each time for 1.5 hours, combine The second decoction is filtered, the filtrate is concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60°C), dried at 80°C, crushed into fine powder, and sieved to obtain the product.

[0065] Preparation of active ingredients: spra...

Embodiment 2

[0073] 1. Preparation of plaster:

[0074] Prescription of raw materials: 6g rose sesame oil, 88g bark of Albizia juliensis, 111g of vine, 80g of cinnamon, 63g of schisandra, 52g of calamus.

[0075] Matrix formula: 37g gelatin, 14g sodium carboxymethylcellulose, 10g polyvinyl alcohol, 307g glycerol, 306g propylene glycol, 50g polyethylene glycol, 50g butanediol, 6g zinc oxide, 6g micronized silica gel, 29g sodium citrate , aluminum trichloride 8g, water 177g.

[0076] Preparation of water extract: same as Example 1.

[0077] Preparation of active ingredients: spray rose balm into the prepared water extract, mix evenly, and obtain Chinese medicine extract powder.

[0078] Preparation of plaster: dissolve the prepared active ingredients in water, add propylene glycol, glycerin, polyethylene glycol and butylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, fully swell, Component 1 is obtained; sodium carboxymethyl ce...

Embodiment 3

[0085] 1. Preparation of plaster:

[0086] Prescription of raw materials: 10g of rose sesame oil, 80g of Albizia Julibrissin, 102g of Caulis japonica, 74g of cinnamon, 60g of schisandra, 74g of Shichangpu.

[0087] Matrix formula: 40g gelatin, 17g sodium carboxymethylcellulose, 17g methylcellulose, 11g sodium polyacrylate, 11g polyvinyl alcohol, 11g polyvinylpyrrolidone, 125g pressure-sensitive adhesive, 33g carbomer, 156g glycerol, Propylene glycol 156g, micropowder silica gel 8g, citric acid 15g, sodium citrate 27g, water 373g.

[0088]Preparation of water extract: same as Example 1.

[0089] Preparation of active ingredients: spray rose balm into the prepared water extract, mix evenly, and obtain Chinese medicine extract powder.

[0090] Preparation of plaster: dissolve the prepared active ingredients in water, add glycerol and propylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, and fully swell to obtain comp...

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Abstract

The invention relates to a traditional Chinese medicine (TCM) compound preparation, in particular to a self-heated TCM emplastrum for improving sleep quality. The self-heated TCM emplastrum comprises a sealing bag, a plaster and a self-heated bag, wherein the plaster and the self-heated bag are wrapped in the sealing bag and are bonded together up and down; the self-heated bag comprises an air-permeable bag and chemical heating materials which are wrapped in the air-permeable bag and are used for iron oxidation-reduction reactions; and the plaster comprises a backing layer, a medicine storagelayer and an anti-adhesion layer. The emplastrum is characterized in that the medicine storage layer comprises a pharmaceutically acceptable matrix and active ingredients of raw medicines; the activeingredients account for 40% of the matrix by weight and comprise 1.5-3% of rose balm and aqueous extracts of the following raw medicines according to the weight percent of the raw medicines: 20-50% of silktree albizzia bark, 20-50% of tuber fleeceflower stem, 10-30% of cinnamon, 5-20% of Chinese magnoliavine fruit and 5-20% of rhizoma acori graminei. The self-heated TCM emplastrum provided by theinvention has the advantages of high effect taking speed, good percutaneous absorption and definite curative effect.

Description

field of invention [0001] The invention relates to medical preparations, in particular to a traditional Chinese medicine compound preparation. technical background [0002] Insomnia is a disease characterized by frequent inability to obtain normal sleep. It is caused by various reasons such as difficulty in falling asleep, too short sleep depth or frequency (shallow sleep insomnia), early awakening, and insufficient sleep time or poor quality. Call it falling asleep and maintaining sleep disorder (D1MS), motherland's medical science is referred to as " insomnia ", " can't sleep ", " can't lie down ", " can't close eyes ". At present, the mechanism of insomnia is not completely clear, and modern medicine has no good prevention and treatment methods for it. However, Chinese medicine has obvious advantages in the prevention and treatment of insomnia. Due to the high incidence of insomnia, it is required that the means and methods of its prevention and treatment must be popula...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/888A61K9/70A61F7/03A61P25/20
Inventor 方永奇方惠新刘林薛中锋方若鸣
Owner GUANGZHOU NEW DESIGN BIOTECHNOLOGY CO LTD