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Self-heating Chinese medicinal adhesive plaster for improving constipation

A self-heating technology that improves constipation and is applied to heating appliances for treatment, drug combinations, and pharmaceutical formulas, etc.

Active Publication Date: 2012-03-14
高康日化集团有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific drug for the treatment of all kinds of constipation, and the medicine of the motherland has obvious advantages in the prevention and treatment of constipation.

Method used

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  • Self-heating Chinese medicinal adhesive plaster for improving constipation
  • Self-heating Chinese medicinal adhesive plaster for improving constipation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] 1. Preparation of plaster:

[0047] Prescription of raw materials: borneol 8g, rhubarb 120g, citrus aurantium 80g, radish seed 60g, achyranthes bidentata 80g, cinnamon 52g.

[0048] Matrix formula: 31g gelatin, 12g sodium carboxymethylcellulose, 8g polyvinyl alcohol, 88g pressure-sensitive adhesive, 24g carbomer, 250g glycerol, 250g propylene glycol, 5g kaolin, 5g zinc oxide, 9g citric acid, citric acid Sodium 33g, water 285g.

[0049] Preparation of water extract: decoct rhubarb, citrus aurantium, radish seed, achyranthes bidentata and cinnamon twice, add 6 times the amount of water for the first time, add 6 times the amount of water for the second time, each time for 1.5 hours, and combine the two The second decoction is filtered, the filtrate is concentrated to a thick paste with a relative density of 1.28-1.32 (measured at 60°C), dried at 80°C, crushed into fine powder, and sieved to obtain.

[0050] Preparation of active ingredients: add borneol to the prepared w...

Embodiment 2

[0058] 1. Preparation of plaster:

[0059] Prescription of raw materials: borneol 6g, rhubarb 90g, citrus aurantium 72g, radish 63g, achyranthes bidentata 106g, cinnamon 63g.

[0060] Matrix formula: 37g gelatin, 14g sodium carboxymethylcellulose, 10g polyvinyl alcohol, 307g glycerol, 306g propylene glycol, 50g polyethylene glycol, 50g butanediol, 6g zinc oxide, 6g micronized silica gel, 29g sodium citrate , aluminum trichloride 8g, water 177g.

[0061] Preparation of water extract: same as Example 1.

[0062] Preparation of active ingredients: add borneol to the prepared water extract, mix well to obtain Chinese medicine extract powder.

[0063] Preparation of plaster: dissolve the prepared active ingredients in water, add propylene glycol, glycerin, polyethylene glycol and butylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, fully swell, Component 1 is obtained; sodium carboxymethyl cellulose is dissolved in 1 / ...

Embodiment 3

[0070] 1. Preparation of plaster:

[0071] Prescription of raw materials: borneol 11g, rhubarb 89g, citrus aurantium 60g, radish seed 60g, achyranthes bidentata 100g, cinnamon 80g.

[0072] Matrix formula: 40g gelatin, 17g sodium carboxymethylcellulose, 17g methylcellulose, 11g sodium polyacrylate, 11g polyvinyl alcohol, 11g polyvinylpyrrolidone, 125g pressure-sensitive adhesive, 33g carbomer, 156g glycerol, Propylene glycol 156g, micropowder silica gel 8g, citric acid 15g, sodium citrate 27g, water 373g.

[0073] Preparation of water extract: same as Example 1.

[0074] Preparation of active ingredients: add borneol to the prepared water extract, mix well to obtain Chinese medicine extract powder.

[0075] Preparation of plaster: dissolve the prepared active ingredients in water, add glycerol and propylene glycol and mix to obtain a mixed solution; dissolve polyvinyl alcohol in 1 / 2 of the above mixed solution, and fully swell to obtain component 1; gelatin, carboxylate Sod...

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Abstract

The invention relates to a compound Chinese medicinal preparation, in particular to a self-heating Chinese medicinal adhesive plaster for improving constipation. The self-heating Chinese medicinal adhesive plaster consists of a sealing bag, and plaster and a self-heating bag which are wrapped in the sealing bag and are adhered vertically, wherein the self-heating bag consists of a permeable bag and a chemical heating material which is wrapped in the permeable bag for iron oxidation-reduction reaction; the plaster consists of a back lining layer, a medicament storage layer and an anti-adhesionlayer; the self-heating Chinese medicinal adhesive plaster is characterized in that: the medicament storage layer consists of a pharmaceutically acceptable substrate and active ingredients of the rawmaterial medicaments which are equivalently 40 percent of the weight of the substrate; the active ingredients consist of 1.5-3 percent of borneol and water extracts of the following raw material medicaments in weight percentage of the raw material medicaments: 20-40 percent of rhubarb, 10-30 percent of immature bitter orange, 10-20 percent of radish seed, 10-30 percent of root of bidentate achyranthes and 10-20 percent of cinnamon. The self-heating Chinese medicinal adhesive plaster has the advantages of quick response, good transdermal absorption and clear curative effect.

Description

field of invention [0001] The invention relates to medical preparations, in particular to a traditional Chinese medicine compound preparation. technical background [0002] Constipation is a common disease in modern society. Its causes are complex and are mostly related to gastrointestinal function, food intake and habits, living habits, environmental factors, and mental state. Traditional Chinese medicine believes that constipation is mainly caused by dryness and heat, stagnation of qi, insufficient body fluid, and deficiency and coldness of the spleen and kidney. At present, there is no specific medicine for treating all kinds of constipation, and Chinese medicine has obvious advantages in the prevention and treatment of constipation. Due to the high incidence of constipation, it is necessary to popularize the means and methods of its prevention and treatment. Therefore, it is an objective need to seek a method of prevention and treatment of constipation that can not only...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61K9/70A61F7/03A61P1/10A61K31/045
Inventor 方永奇方惠新刘林薛中锋方若鸣
Owner 高康日化集团有限公司
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