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Veterinary medicinal preparation for treating colibacillosis and preparation method thereof

A technology of colibacillosis and veterinary medicine, which is applied in the field of veterinary medicine, can solve the problems that powders are not easy to feed, delay the disease of livestock and poultry, and economic loss, and achieve the effect of not being easy to drug resistance, avoiding the loss of active ingredients, and delaying the disease

Active Publication Date: 2013-11-27
河北康利动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the powder is not easy to feed during actual use. On the other hand, due to the short intestinal tract of the chicken, the active ingredients are excreted with the powder before it dissolves, which is likely to cause waste of medicines, delay the condition of livestock and poultry, and bring unnecessary economic loss

Method used

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  • Veterinary medicinal preparation for treating colibacillosis and preparation method thereof
  • Veterinary medicinal preparation for treating colibacillosis and preparation method thereof
  • Veterinary medicinal preparation for treating colibacillosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A veterinary medicine preparation for treating colibacillosis, the weight ratio of Pulsatilla chinensis, Gentiana and Coptidis Rhizoma in raw materials is 6:3:1.

[0040] The preparation method comprises the following steps:

[0041] (1) Extraction of active ingredients

[0042] Extract the active ingredients of gentian and coptis for the first time: put 3 parts by weight of gentian and 1 part by weight of coptis into an alcohol extraction tank, add ethanol to soak for 12 hours, the weight of ethanol is 4 parts of the sum of the weight of gentian and coptis times, the concentration of ethanol is 70% (V / V), after soaking, the gentian and coptis dregs are separated to obtain the alcohol extract of gentian and coptis for the first time;

[0043] The second extraction of active ingredients of gentian and coptis: extract the active ingredients from the separated gentian and coptis dregs, the concentration and weight of the ethanol used and the soaking time are the same as w...

Embodiment 2

[0131] A veterinary drug preparation for treating colibacillosis, the weight ratio of Pulsatilla chinensis, Gentian and Coptis chinensis in raw materials is 90:65:14.

[0132] The preparation method comprises the following steps:

[0133] (1) Extraction of active ingredients

[0134] Extract the active ingredients of gentian and coptis for the first time: put 65 parts by weight of gentian and 14 parts by weight of coptis into an alcohol extraction tank, add ethanol to soak for 24 hours, and the weight of ethanol is 2 times the weight of gentian and coptis. times, the concentration of ethanol is 80% (V / V), after soaking, the gentian and coptis dregs are separated to obtain the alcohol extract of gentian and coptis for the first time;

[0135] The second extraction of active ingredients of gentian and coptis: extract the active ingredients from the separated gentian and coptis dregs, the concentration and weight of the ethanol used and the soaking time are the same as when the ...

Embodiment 3

[0149] A veterinary medicine preparation for treating colibacillosis, the weight ratio of Pulsatilla chinensis, Gentian and Coptidis Rhizoma in raw materials is 13:4:1.

[0150] The preparation method comprises the following steps:

[0151] (1) Extraction of active ingredients

[0152] Extract the active ingredients of gentian and coptis for the first time: put 4 parts by weight of gentian and 1 part by weight of coptis into an alcohol extraction tank, add ethanol to soak for 2 hours, and the weight of ethanol is 6 times the weight of gentian and coptis. times, the concentration of ethanol is 60% (V / V), after soaking, the gentian and coptis dregs are separated to obtain the alcohol extract of gentian and coptis for the first time;

[0153] The second extraction of active ingredients of gentian and coptis: extract the active ingredients from the separated gentian and coptis dregs, the concentration and weight of the ethanol used and the soaking time are the same as when the ac...

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Abstract

The invention discloses a veterinary medicinal preparation for treating colibacillosis and a preparation method thereof, and belongs to the field of veterinary drugs. The veterinary medicinal preparation for treating colibacillosis is a liquid preparation and is prepared from traditional Chinese medicines of anemone root, radix gentianae and coptis through active ingredient extraction, condensation, deposition and filtration. The preparation method comprises the following steps of 1, active ingredient extraction comprising primary alcohol extraction of active ingredients of radix gentianae and coptis, secondary alcohol extraction of active ingredients of radix gentianae and coptis, primary water extraction of active ingredients of anemone root, radix gentianae and coptis, and secondary water extraction of active ingredients of anemone root, radix gentianae and coptis, 2, condensation comprising concentrating the extract obtained by the step 1, 3, deposition and 4, filtration. The veterinary medicinal preparation for treating colibacillosis is a pure traditional Chinese medicine preparation, produces a small amount of medicinal residues, does not produce drug resistance easily, does not produce pollution, does not have a withdrawal period, has a low use cost, does not have toxicity, can be used for livestock and poultry conveniently, and is suitable for prevention and treatment on colibacillosis. The preparation method adopts an extraction method combining water extraction and alcohol extraction and thus active ingredient content is improved.

Description

technical field [0001] The invention relates to a veterinary drug preparation for treating colibacillosis and a preparation method thereof, belonging to the field of veterinary drugs. Background technique [0002] Veterinary medicine Bailongsan consists of Pulsatilla, Coptidis and Gentian. Pharmacological studies of modern Chinese medicine have shown that Pulsatilla fresh juice and decoction have significant inhibitory effects on a variety of bacteria, and have significant inhibitory effects on various intestinal pathogenic bacteria such as Shigella. white. Pulsatilla's antibacterial activity has a synergistic effect with streptomycin. Coptidis rhizome has anti-ulcer, inhibiting gastric acid secretion, the strength is equivalent to cimetidine, protecting gastric mucosa, anti-inflammatory, analgesic, antibacterial, etc. Its main component, berberine, has a wide antibacterial spectrum and no cross-resistance to penicillin and streptomycin. Medicinal properties. Gentiana h...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/718A61P31/04
Inventor 赵凤玲
Owner 河北康利动物药业有限公司