Blood analysis micro system

Abstract

A blood analysis micro system with multiple ion sensing functions is manufactured by using a micro electro mechanical system (MEMS) process and a packaging technology. The blood analysis micro system is provided with an integrated miniature reference electrode, thus the size of a chip is miniaturized. The blood analysis micro system is provided with a grid sensing region larger than a planar ion selection electrode (Planar ISE) or an ion sensing filed effect transistor (ISFET), thus unnecessary signal interference can be effectively avoided, and possibility of packaging difficulty and liquid leakage is reduced. Therefore, the blood analysis micro system has the advantages of light weight, thinness, short size, high reaction speed, high precision, lower cost and high compatibility with an IC process, and has excellent electrochemical properties such as extremely high long-term potential stability, extremely low offset-compensating potential, small alternating current impedance, stable dynamic reference potential, low electrochemical noise, high electrode reproducibility and the like.

Description

technical field [0001] The present invention relates to a blood analysis microsystem, more specifically to a blood analysis microsystem containing miniature silver chloride reference electrodes. Background technique [0002] In recent years, with the rapid development of bioinformatics analysis technology in the fields of hematology, biochemistry, and microbiology, the demand for key nursing inspection and analysis systems has increased. Miniaturizing critical care inspection components using existing IC or MEMS technology has several advantages: shorter response time, less sampling requirements, smaller size, lower power consumption, and lower cost. [0003] In the prior art, there is a lack of a blood analysis microsystem capable of simultaneously detecting the concentrations of sodium, potassium, hydrogen, calcium and ammonium in human serum. These ion concentration data are very important reference information for medical personnel to care for some critically ill patien...

AI Technical Summary

Problems solved by technology

However, the existing ion sensors are large in size, and one ion sensor can only detect the concentration of a single ion

Moreover, existing miniature ion sensors usually need to be used with commercial reference electrodes in practical applications, and the volume of some existing reference electrodes is about hundreds of times larger than that of miniature ion sensors, so even if the ion sensors are miniaturized, the size of the entire system still can't get smaller

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