Temperature-sensitive polymer/gold nanoparticle hybrid microspheres and preparation method thereof

Abstract

The invention relates to temperature-sensitive polymer / gold nanoparticle hybrid microspheres and a preparation method thereof. The temperature-sensitive polymer / gold nanoparticle hybrid microspheres consist of more than 99.9 weight percent of polymer and less than 0.1 weight percent of gold nanoparticles. The preparation method comprises the following steps of: a) preparing a 2-(methoxycarbonyl)-ethyldithiophenyl ester chain transfer agent; b) synthesizing an N-isopropylacrylamide macromolecular chain transfer agent by using 2-(methoxycarbonyl)-ethyldithiophenyl ester obtained in step a) and azodiisobutyronitrile; c) further polymerizing 4-vinylpyridine by using the macromolecular chain transfer agent obtained in step b) and the azodiisobutyronitrile to obtain a block copolymer; d) preparing polymer microsphere suspension by using the block copolymer obtained in step (c); and e) adding chloroauric acid into the microsphere suspension, and reducing by using excessive sodium borohydride to obtain the temperature-sensitive hybrid polymer microspheres. The temperature-sensitive polymer / gold nanoparticle hybrid microspheres overcome the disadvantages that the gold nanoparticles are not firmly combined and are easy to fall off and the catalytic activity is not adjustable, and can be used for the fields of controllable catalysis and the like.

Description

technical field

[0001] The invention belongs to the field of polymer science and technology, in particular to a polymer / gold nanoparticle hybrid intelligent microsphere and a preparation method thereof. Background technique

[0002] Gold nanoparticles have unique stability related to size, small size effect, quantum effect, surface effect and biological affinity. As a good classical nanomaterial, it is a research hotspot in optics, electronics, catalysis and biomedicine. Ideal gold nanomaterials or composite materials require gold nanoparticles with limited size and shape, modified organic and / or biomolecules on the surface, special composite structures (such as core-shell structure) and the ability to be in 2-D or 3D. Ordered arrangements in -D space or devices, which often have different properties than individual particles and macroscopic entities. Therefore, it is a research trend in this field to synthesize gold nanoparticle carriers with special structures and develo...