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Desensitizing toothpaste and desensitizing day-and-night combined toothpaste

A desensitizing toothpaste and raw material technology, applied in the field of oral care, can solve the problems of low effective content of the desensitizing agent composition, small desensitizing agent content, and inability to maintain effective solubility of the desensitizing agent

Active Publication Date: 2013-07-17
广州舒客实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In the current desensitizing compositions and methods for treating dentin hypersensitivity and enamel demineralization, the effective content of the desensitizing agent composition is not high, so that the content of the desensitizing agent capable of exerting an antisensitizing effect is small, and the effect is not obvious
At the same time, one of the important reasons is that the desensitizer cannot maintain effective solubility in the oral cavity for a long time

Method used

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  • Desensitizing toothpaste and desensitizing day-and-night combined toothpaste
  • Desensitizing toothpaste and desensitizing day-and-night combined toothpaste
  • Desensitizing toothpaste and desensitizing day-and-night combined toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] A desensitizing toothpaste, the formula is as follows:

[0070] Sorbitol 18 parts

[0071] Calcium carbonate 48 parts

[0072] Hydrated silica 2 parts

[0073] PEG-12 4 parts

[0074] Sodium lauryl sulfate 2.4 parts

[0075] 3 parts strontium chloride

[0076] Carboxymethylcellulose 1.0 parts

[0077] Xanthan gum 0.2 parts

[0078] Tetrasodium pyrophosphate 0.1 parts

[0079] Sodium saccharin 0.2 parts

[0080] Methylparaben 0.2 parts

[0081] Essence 1.2 parts

[0082] 19.7 parts of deionized water

[0083] Dissolve sodium saccharin and tetrasodium pyrophosphate in deionized water and dissolve. Then add sorbitol, polyethylene glycol-12, hydroxymethylcellulose, xanthan gum, and disperse evenly. Add calcium carbonate, hydrated silica, sodium lauryl sulfate, strontium chloride. Dissolve the methylparaben in the essence, add it into the cream, and emulsify fully.

Embodiment 2

[0085] Use a desensitizing toothpaste formula in the morning:

[0086] Sorbitol 18 parts

[0087] Calcium carbonate 48 parts

[0088] Hydrated silica 2 parts

[0089] PEG-12 4 parts

[0090] Sodium lauryl sulfate 2.4 parts

[0091] 3 parts strontium chloride

[0092] Carboxymethylcellulose 1.0 parts

[0093] Xanthan gum 0.2 parts

[0094] Tetrasodium pyrophosphate 0.1 parts

[0095] Sodium saccharin 0.2 parts

[0096] Methylparaben 0.2 parts

[0097] Essence 1.2 parts

[0098] 19.7 parts of deionized water

[0099] Use a desensitizing toothpaste formula at night to implement the ratio:

[0100] Sorbitol 20 parts

[0101] Calcium carbonate 41 parts

[0102] Hydrated silica 2 parts

[0103] PEG-12 4 parts

[0104] Sodium lauryl sulfate 2.4 parts

[0105] Strontium chloride 2.5 parts

[0106] Hydroxyethyl cellulose 1.0 parts

[0107] Tetrasodium pyrophosphate 0.1 parts

[0108] Xanthan gum 0.2 parts

[0109] Sodium saccharin 0.2 parts

[0110] Methylparaben ...

Embodiment 3

[0117] Desensitized toothpaste formula implementation ratio:

[0118] Sorbitol 70 parts

[0119] Calcium carbonate 15 parts

[0120] Hydrated silica 3 parts

[0121] PEG-12 4 parts

[0122] Sodium lauryl sulfate 1.2 parts

[0123] Strontium acetate 0.1 parts

[0124] Hydroxyethyl cellulose 0.4 part

[0125] Tetrasodium pyrophosphate 0.05 parts

[0126] Xanthan gum 0.4 parts

[0127] Sodium saccharin 0.2 parts

[0128] Methylparaben 0.01 parts

[0129] Essence 0.3 parts

[0130] PVA / MA copolymer 0.001 parts

[0131] Zinc citrate 0.009 parts

[0132] 5.33 parts of deionized water

[0133] Dissolve sodium saccharin and tetrasodium pyrophosphate in deionized water and dissolve. Then add sorbitol, polyethylene glycol-12, hydroxyethyl cellulose, xanthan gum, and disperse evenly. Calcium carbonate, hydrated silica, sodium lauryl sulfate, strontium acetate, and a mixture of vinyl methyl ether / maleic anhydride copolymer and zinc citrate were added. Dissolve the methylparab...

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Abstract

The invention discloses desensitizing toothpaste and desensitizing day-and-night combined toothpaste. The desensitizing toothpaste comprises the following desensitizing composites in part by weight: 0.01 to 5 parts of vinyl methyl ether / maleic anhydride copolymer, 0.01 to 5 parts of zinc citrate and 0.1 to 4 parts of strontium salt, wherein the weight ratio of the vinyl methyl ether / maleic anhydride copolymer to the zinc citrate is (30:1)-(1:1). According to the desensitizing toothpaste, the copolymer forms a biomembrane on surfaces of teeth, so that a strontium salt desensitizer serving as an active ingredient is released slowly, and the desensitizer keeps active concentration for a long time in an oral cavity and acts on dentine permanently to block a patulous tubule of the dentine. Simultaneously, the effects of nourishing gums and inhibiting dental plaques by the zinc citrate are released slowly, so that the oral cavity can be protected for a long time.

Description

technical field [0001] The invention relates to the field of oral care, in particular to a desensitizing toothpaste and a desensitizing combined morning and evening toothpaste. Background technique [0002] Epidemiological surveys show that about 29.7% of adults in my country have different degrees of dentin hypersensitivity. There are many reasons for dentin sensitivity: including various pathological and physiological factors that cause loss of enamel or cementum and exposure of dentin, such as: abrasion, gingival recession, improper brushing methods, excessive intake of acidic foods, etc. With the development of the economy and the improvement of people's living standards, more and more people begin to pay attention to oral health issues. [0003] At present, there are many clinical methods for treating dentin sensitivity, among which local application of anti-sensitivity toothpaste containing some special ingredients is the first choice for patients. It is also the fir...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/81A61K8/86A61Q11/00A61K8/20A61K8/24A61K8/36A61K8/365
Inventor 陈敏珊吴远陈素珍甘海波
Owner 广州舒客实业有限公司
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