Oligopeptide with breast cancer resistant activity and application thereof

An anti-breast cancer and breast cancer cell technology, applied in oligopeptides and their applications, oligopeptides with anti-breast cancer activity and their applications, can solve the problems of long cycle and high cost, and achieve growth inhibition, small molecular weight, and inhibition proliferating effect
CN102532268AInactive Publication Date: 2012-07-04ZHUHAI JINLONG BIOTECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHUHAI JINLONG BIOTECH CO LTD
Publication Date
2012-07-04
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses an oligopeptide with breast cancer resistant activity. The oligopeptide has a sequence of His-Asn-Tyr-Gly-Phe-Val-Pro-Ser-Leu. The oligopeptide can selectively inhibit the growth of in-vitro breast cancer cells under low concentration and does not have any influence on normal breast cells. In-vivo experiments show that the oligopeptide has a strong effect of inhibiting the growth and proliferation of cancer cells and has an obvious dose-effect relationship. Because of a safe, efficient and ideal anti-cancer effect, the oligopeptide can be used for preparing anti-cancer medicines and has a good application prospect.
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Description

[0001] technical field

[0002] The present invention relates to oligopeptide and its application, in particular to an oligopeptide with anti-breast cancer activity and its application, which belongs to the field of biomedicine.

[0003] Background technique

[0004] Breast cancer is the main malignant tumor that endangers women's health. About 1.2 million women in the world develop breast cancer every year, accounting for 18% of all tumors in women. The 5-year survival rate of breast cancer is about 50%-60%, nearly 50% of patients relapse and metastasize after treatment, and the average survival time of patients with advanced breast cancer is only 18-30 months. Breast cancer treatment methods include surgery, radiotherapy, chemotherapy, endocrine therapy and other traditional treatments. However, the risk of surgical treatment is high, the trauma to the human body is large, the patient's immunity is reduced, and the resistance to the disease is reduced. A series of surgic...

Claims

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