Laser early cancer diagnosis instrument

Abstract

The invention discloses a laser early cancer diagnosis instrument. An optical path between a laser (1) and an optical fiber coupler (6) of the diagnosis instrument is arranged thereon with a frequency doubler (2), a frequency mixer (3), a frequency divider (4) and a filter (5) in sequence. An optical path of the frequency divider (4) is arranged thereon with a photoelectric converter (11) for providing collected triggering signals. A conduction optical fiber (7) consists of an incident optical fiber (71) and a receiving optical fiber (72). A bandpass filter (9) for receiving fluorescence signals and a photoelectric detector (10) are arranged between the receiving optical fiber (72) and a computer (12). The computer (12) is electrically connected with the laser (1), the photoelectric converter (11), the photoelectric detector (10) and an output unit (13), and is used for controlling the laser (1), subjecting the collected fluorescence signals to integral processing by using a time domain method and sending a comparison result of the processed fluorescence signals and a fluorescence signal of a normal tissue to the output unit (12) to be displayed. The diagnosis instrument can effectively diagnose various early cancers.

Description

technical field [0001] The invention relates to a diagnostic instrument, in particular to a laser early cancer diagnostic instrument. Background technique [0002] Since Alfano et al. discovered in 1984 that low-power lasers could induce autofluorescence in breast and lung tissues, and Richards et al. used lasers with a wavelength of 290-600 nm to induce autofluorescence in colonic mucosal tissue, many scholars have begun to study the use of laser-induced fluorescence (laser-induced fluorescence). Induced fluorescence (LIF) technology for spectral analysis to diagnose early colorectal malignant tumors. LIF technology has proposed a new and effective diagnostic approach and method in the early diagnosis of colorectal cancer, and has made great progress in the early diagnosis of colorectal cancer and precancerous lesions, and created a new tumor detection method-light biopsy. At present, LIF diagnostic instruments are mostly composed of excitation light source, conductive op...

AI Technical Summary

Problems solved by technology

At present, LIF diagnostic instruments are mostly composed of excitation light source, conductive optical fiber, optical coupler, polychromator, optical multi-channel analysis system (OMA) and computer. It is 100% and the negative coincidence rate is 94%. It provides a relatively reliable means for early diagnosis and treatment of colorectal cancer, but there are also insurmountable deficiencies. secondly, because the detected fluorescence spectrum line is too weak and unclear, so the professional technical level of the operator is very high; thirdly, the whole set of equipment is expensive, more than 1 million yuan, which makes its popularization and application and industry It is difficult to carry out the transformation, which leads to the lack of competitiveness of products in the market

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