Unlock instant, AI-driven research and patent intelligence for your innovation.

Beta-amino ethyl thiosulfuric acid and synthesis method thereof

A technology of aminoethyl thiosulfuric acid and feed additives, applied in animal feed, animal feed, organic chemistry, etc., can solve problems such as obesity and affecting meat quality, and achieve increased reaction temperature, improved safety, and product yield high effect

Active Publication Date: 2014-01-15
广东有机宝生物科技股份有限公司 +1
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Due to the rich nutrition of the feed, small range of activities, and variety variation, artificially raised animals are often overly obese, with more fat and less lean meat, which seriously affects the quality of meat

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Beta-amino ethyl thiosulfuric acid and synthesis method thereof
  • Beta-amino ethyl thiosulfuric acid and synthesis method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The synthetic method 1 of β-aminoethylthiosulfuric acid, concrete steps are:

[0028] 1) Preparation of ethyl chloride hydrochloride:

[0029] Add 150g of ethanolamine hydrochloride to the reaction vessel, then add 300g of anhydrous chlorobenzene, stir evenly, keep the temperature at 80°C, add 450g of thionyl chloride dropwise at a rate of 1.5g / min, and continue stirring for 1 hour after dropping , then cooled to 30°C, added 210 ml of water, 7.5 g of activated carbon, stirred for 0.5 h, discharged and filtered, and the filtrate was allowed to stand for stratification.

[0030] 2) Preparation of β-aminoethylthiosulfuric acid

[0031] Take the lower layer of ethyl chloride hydrochloride solution, 45 ~ 55 ℃ rotary evaporation under reduced pressure until anhydrous, to obtain a viscous liquid, control the temperature at 70 ℃, add 600g of sodium thiosulfate, keep stirring for 2 hours and then quickly filter while hot , the filtrate was cooled to 10°C, crystallized, filtere...

Embodiment 2

[0033] The synthetic method 2 of β-aminoethyl thiosulfuric acid, concrete steps are:

[0034] 1) Preparation of ethyl chloride hydrochloride:

[0035] In reaction vessel, add 160g ethanolamine hydrochloride, then add 320 g Anhydrous chlorobenzene, stir evenly, keep the temperature at 80°C, add 480g of thionyl chloride dropwise at a rate of 1.5g / min, continue stirring for 1 hour after dropping, then cool to 30°C, add 220ml of water, 8.0g Activated carbon, after stirring for 0.5h, discharge and filter, and the filtrate is allowed to stand for stratification.

[0036] 2) Preparation of β-aminoethylthiosulfuric acid

[0037] Take the lower layer of ethyl chloride hydrochloride solution, 45 ~ 55 ℃ rotary evaporation under reduced pressure until anhydrous, to obtain a viscous liquid, control the temperature at 70 ℃, add 640g of sodium thiosulfate, keep stirring for 2 hours, then quickly filter while hot , the filtrate was cooled to 10°C, crystallized, filtered, and the solid was ...

Embodiment 3

[0039] The synthetic method 3 of β-aminoethylthiosulfuric acid, concrete steps are:

[0040] 1) Preparation of ethyl chloride hydrochloride:

[0041] Add 170g ethanolamine hydrochloride in reaction vessel, add 340 g Anhydrous chlorobenzene, stir evenly, keep the temperature at 80°C, add 510g of thionyl chloride dropwise at a rate of 1.5g / min, continue stirring for 1 hour after dropping, then cool to 30°C, add 230ml of water, 8.5g Activated carbon, after stirring for 0.5h, discharge and filter, and the filtrate is allowed to stand for stratification.

[0042] 2) Preparation of β-aminoethylthiosulfuric acid

[0043] Take the lower layer of ethyl chloride hydrochloride solution, 45 ~ 55 ℃ rotary evaporation under reduced pressure until anhydrous, to obtain a viscous liquid, control the temperature at 70 ℃, add 680g of sodium thiosulfate, keep stirring for 2 hours and then quickly filter while hot , the filtrate was cooled to 10°C, crystallized, filtered, and the solid was drie...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a new compound namely beta-amino ethyl thiosulfuric acid. According to the invention, the molecular formula of beta-amino ethyl thiosulfuric acid is NH2CH2CH2S2O3H, and the molecular structure of beta-amino ethyl thiosulfuric acid is shown in a formula (I). Beta-amino ethyl thiosulfuric acid has the effects of promoting growth of animals, improving lean meat percentage and reducing fat percentage, and can be used as an animal feed additive. The invention also discloses a synthesis method of beta-amino ethyl thiosulfuric acid. In the synthesis method, chlorobenzene is used as a solvent for preparing chloroethylamine monohydrochloride; and because the boiling point of chlorobenzene is high, a phenomenon that the solvent severely refluxes when the reaction is carried out is avoided, safety is improved, and reaction temperature is properly improved, thus conversion rate is improved and the yield of a product is high.

Description

technical field [0001] The present invention relates to the synthetic method of β-amino ethyl thiosulfuric acid. Background technique [0002] Due to the rich nutrition of the feed, the small range of activities, and the variation of the species, the artificially raised animals are often too obese, with more fat and less lean meat, which seriously affects the quality of the meat. Therefore, in order to increase the lean meat rate of animals, producers artificially add "lean meat powder" to the feed, resulting in an increase in the lean meat percentage, but this "clean meat powder" contains harmful ingredients to the human body. Therefore, it is of great social significance to develop a feed additive that can increase the lean meat content of animals and has no side effects on the human body. [0003] Cysteamine (CS), also known as β-mercaptoethylamine, is equivalent to the decarboxylation product of cysteine ​​and is a component of acetic acid coenzyme A. It has a variety o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C07C381/02A23K1/16
Inventor 舒绪刚高均勇许祥印遇龙
Owner 广东有机宝生物科技股份有限公司