Vaccine cryoprotectant without composition of gelatin and human albumin
A technology for freeze-drying protective agent and human blood, which can be applied to medical preparations without active ingredients, medical preparations containing active ingredients, and antibody medical ingredients, etc. Harmful, low cost, good safety effect
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Embodiment 1
[0017] Weigh the following substances (g / l): dextran (40) 50, sucrose 50, lactose 20, mannitol 10, glycine 10, arginine 1.85, sodium glutamate 9.2, urea 4.6, 199 comprehensive medium 2, Fully dissolve the above-mentioned substances in an appropriate amount of sterilized water for injection, then constant volume, measure the osmotic pressure within the range of 300-450mosm, adjust the pH with 1N hydrochloric acid to within the range of 7.2-7.8, and finally sterilize and filter to obtain the obtained product.
Embodiment 2
[0019] Weigh the following substances (g / l): dextran (40) 20, sucrose 30, lactose 10, mannitol 5, glycine 5, arginine 1.85, sodium glutamate 9.2, urea 4.6, 199 comprehensive medium 2, Fully dissolve the above-mentioned substances in an appropriate amount of sterilized water for injection, then constant volume, measure the osmotic pressure within the range of 300-450mosm, adjust the pH with 1N hydrochloric acid to within the range of 7.2-7.8, and finally sterilize and filter to obtain the obtained product.
Embodiment 3
[0021] Weigh the following substances (g / l): dextran (40) 60, sucrose 60, lactose 25, mannitol 15, glycine 15, arginine 1.85, sodium glutamate 9.2, urea 4.6, 199 comprehensive medium 2, Fully dissolve the above-mentioned substances in an appropriate amount of sterilized water for injection, then constant volume, measure the osmotic pressure within the range of 300-450mosm, adjust the pH with 1N hydrochloric acid to within the range of 7.2-7.8, and finally sterilize and filter to obtain the obtained product.
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