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Composition with effect of treating diabetes and preparation method and application thereof

A composition and technology for diabetes, applied in the field of medicine, can solve the problems of compound medicine with large taste and quantity, inconsistent treatment principles, etc., and achieve the effects of no toxic and side effects, good blood sugar control, and strong operability.

Inactive Publication Date: 2013-11-06
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, traditional Chinese medicines for diabetes are mostly single prescriptions and proven prescriptions, and compound prescriptions have a large amount of medicine, and the basis of traditional Chinese medicine prescriptions is different, and the treatment principles are not uniform. Therefore, based on traditional Chinese medicine, according to the pathogenesis of diabetes, actively seek and work hard to explore the treatment of this disease Efficient and non-toxic

Method used

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  • Composition with effect of treating diabetes and preparation method and application thereof
  • Composition with effect of treating diabetes and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Remove the clam shells, wash the soft body, add 2 times the amount of water and decoct twice for 40 minutes each time, combine the extracts and filter, collect the supernatant, concentrate, cool the concentrated solution, add ethanol for precipitation, until the ethanol precipitation The mass percentage in the system is 70%, filtered to obtain ethanol precipitate, and dried under reduced pressure at a temperature of 50-55°C to obtain the extract of clam four horns; take mulberry leaves, add 10 times the amount of water to extract twice, Each time for 1 hour, combine the extracts, filter, concentrate to obtain the extract, crush to obtain the mulberry leaf extract; mix the four-cornered clam extract and the mulberry leaf extract at a weight ratio of 1:10, and mix with lactose and cornstarch All mixed with whole grains, and then packed into capsules to make capsules.

Embodiment 2

[0031] Remove the clam shells, wash the soft body, add 6 times the amount of water to decoct 3 times, 30 minutes each time, combine the extracts and filter, collect the supernatant, concentrate, cool the concentrate, add ethanol precipitation, until ethanol precipitation The mass percentage in the system is 75%, filtered to obtain ethanol precipitate, and dried under reduced pressure at a temperature of 50-55°C to obtain the extract of clam four horns; take mulberry leaves, add 8 times the amount of water to extract 3 times, For 2 hours each time, combine the extracts, filter, concentrate to obtain the extract, and crush to obtain the mulberry leaf extract; mix the four-cornered clam extract and the mulberry leaf extract in a weight ratio of 10:1, and then add diluent lactose or corn The starch is mixed evenly, granulated, and dried to make granules.

Embodiment 3

[0033] Remove the clam shell, wash the soft body, add 8 times the amount of water to decoct twice, 60 min each time, combine the extracts and filter, collect the supernatant, concentrate, cool the concentrated solution, add ethanol precipitation, until ethanol precipitation The mass percent content in the system is 65%, filtered to obtain ethanol precipitate, dried under reduced pressure at a temperature of 50-55°C to obtain the extract of clam four horns; take mulberry leaves, add 6 times the amount of water to extract twice, For 4 hours each time, combine the extracts, filter, concentrate to obtain extracts, and crush them to obtain mulberry leaf extracts; mix the four-cornered clam extract and mulberry leaf extract in a weight ratio of 6:1, and then add diluent lactose or corn The starch is mixed evenly, granulated, dried, and made into pills.

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Abstract

The invention discloses a composition with an effect of treating diabetes and a preparation method and application thereof. The composition consists of the following raw materials in parts by weight: 1 to 10 parts of mactra veneriformis extract, and 1 to 10 parts of mulberry leaf extract. The Chinese medicaments of the composition are proportioned according to the traditional Chinese medicine theory by adopting the differential treatment theory; and experiment results show that the composition can effectively correct glucose metabolic disorder, reduce blood sugar, improve the function of islet B cells, improve the resistance of the insulin and improve the sugar resistance and can be developed into a new medicament for preventing and treating the diabetes.

Description

technical field [0001] The invention relates to a medicine, in particular to a composition capable of treating diabetes, its preparation method and its application. Background technique [0002] Today, diabetes has become the "third killer" that threatens human beings after cardiovascular and cerebrovascular diseases and tumors on a global scale. No matter in developed or developing countries, the incidence of diabetes is rising sharply. According to the data released by the World Health Organization, there were 30 million diabetic patients in the world in 1985, and it had increased to 135 million by 1997. According to the prediction of international authoritative diabetes epidemiology experts, by 2050, there will be 300 million people with diabetes in the world, and the growth rate of patients in Asia is very fast. . The disease not only brings great pain to the patients, but also greatly affects the quality of life, even threatens the lives of the patients, and also brin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/605A61P3/10A61K35/56A61K35/618
Inventor 吴皓刘睿卞慧敏程建明王令充林瑛
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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