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Medicine composition for treating diabetic nephropathy and preparation method of medicine composition

A technology for diabetic nephropathy and composition, which can be used in drug combinations, pharmaceutical formulations, urinary system diseases, etc., can solve the problems of lack of in-depth research on the pharmacological mechanism of action and renal insufficiency.

Active Publication Date: 2012-09-19
石家庄平安医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if timely and effective treatment is not obtained, kidney damage will gradually develop, eventually leading to the occurrence of renal insufficiency
So far, the exact pathogenesis of diabetic nephropathy has not been fully elucidated, and there is no effective treatment in modern medicine. At present, most studies are still in the stage of reporting clinical efficacy, and there is a lack of in-depth research on its pharmacological mechanism. The pathogenesis of kidney disease is a key topic in the medical field today

Method used

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  • Medicine composition for treating diabetic nephropathy and preparation method of medicine composition
  • Medicine composition for treating diabetic nephropathy and preparation method of medicine composition
  • Medicine composition for treating diabetic nephropathy and preparation method of medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] A pharmaceutical composition for treating diabetic nephropathy. The main active ingredients of the pharmaceutical composition are: Astragalus 336; Rehmannia glutinosa 252; Cornus officinalis (manufactured) 168; Salvia miltiorrhiza 252; Fuzi (manufactured) 84; Poria 252; Yam 84; Chuanxiong 126; Angelica 126; Curcuma 84; Motherwort 252. Its preparation steps include:

[0042] A. Weigh each medicinal raw material according to the above formula, wherein the five flavors of Cornus officinalis (made), Salvia miltiorrhiza, Rhizoma Chuanxiong, Angelica and Curcuma are pulverized into coarse powder;

[0043] B. Astragalus, rehmannia glutinosa, aconite (manufactured), Poria cocos, yam, and motherwort, add water and decoct twice, 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.15g / ml~1.25g / ml ml (50-60°C) clear paste;

[0044] C. Add the coarse powder obtained in step A to the clear paste obtained in step B, mix well, a...

Embodiment 2

[0047] A pharmaceutical composition for treating diabetic nephropathy. The main active ingredients of the pharmaceutical composition are: Astragalus 330; Rehmannia glutinosa 250; Cornus officinalis (manufactured) 170; Salvia miltiorrhiza 258; Fuzi (manufactured) 89; Poria cocos 250; Chinese yam 89; Chuanxiong 130; Angelica 122; Curcuma 86;

[0048] Its preparation steps are: according to the above formula, take each medicinal raw material, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoction, filter, condense into a thick paste, granulate, dry, Instantly.

[0049] In addition, honey or other pharmaceutically acceptable excipients can be added to the dry paste, thick paste or powder mixture prepared in the above embodiments of the present invention to make pills or other clinically acceptable granules, dropping pills, tablets, Capsules, suspensions, oral liquid preparations, etc.

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Abstract

The invention discloses a medicine composition for treating diabetic nephropathy. The prepared medicine composition comprises the following main medicine effect raw materials in parts by weight: 300 to 400 parts of astragalus mongholicus, 200 to 300 parts of prepared rehmannia root, 100 to 200 parts of dogwood, 200 to 300 parts of salvia miltiorrhiza, 50 to 150 parts of monkshood, 200 to 300 parts of poria cocos, 50 to 150 parts of Chinese yam, 100 to 200 parts of ligusticum wallichii, 100 to 200 parts of angelica sinensis, 50 to 150 parts of curcuma zedoary and 200 to 300 parts of leonurus. A preparation method of the medicine composition comprises the steps that: all medicine effect raw materials are weighed according to the recipe and are uniformly mixed through pulverization, water extraction concentration or a pulverization and water extraction concentration combination mode, and the medicine composition is prepared. The medicine composition disclosed by the invention can warm the kidney, strengthen the spleen, activate the blood and promote the diuresis, and is used for patients in the clinical stage of the diabetic nephropathy and patients with the symptoms of deep thready pulse, white fur, dark tongue nature, slight face and double lower limb edema, anorexia and loose stool, sallow complexion or paleness, no luster, dizziness insomnia and lassitude caused by spleen andkidney deficiency and collaterals stasis resistance.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a medicine preparation for warming the kidney, invigorating the spleen, promoting blood circulation and diuresis, which is made from plant Chinese herbal medicines; the invention also relates to a preparation method of the medicine preparation. Background technique [0002] At present, with the improvement of people's living standards and the increase of work pressure, the incidence of diabetes is increasing year by year. In my country, there are about 45 million diabetic patients, and the incidence of diabetic nephropathy accounts for about 20% of diabetic patients. It is one of the main causes of chronic renal failure and seriously endangers the health of patients. At present, Western medicine mainly focuses on controlling diet, controlling blood sugar and blood pressure to treat the primary disease, but the curative effect is not good. There is currently no specific drug tr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P3/10A61P13/12
Inventor 黄怀鹏王占平宫彩霞陶君李静涵
Owner 石家庄平安医院有限公司
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