Simulated moving bed for chromatography device

A technology of simulated moving bed and chromatographic chromatography, which is applied in the field of material separation, can solve the problems that the filler and the fluid cannot move relative to each other, and cannot be used as a simulated moving bed, so as to achieve the effect of improved separation efficiency and simple expansion process

Inactive Publication Date: 2012-09-19
阮立昂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The relative inability of the packing and the fluid to move prevents the technique from being used as a simulated moving bed, which is known to improve the efficiency of batch-processed continuous chromatographic separations

Method used

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  • Simulated moving bed for chromatography device
  • Simulated moving bed for chromatography device
  • Simulated moving bed for chromatography device

Examples

Experimental program
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Embodiment 1

[0059] Such as figure 1 As shown, in the simulated moving bed chromatography device in this embodiment, there is fluid radial flow in each stationary phase packed bed.

[0060] Such as figure 2 As shown, it is a side view of the simulated moving bed chromatography device with two static pipelines in this embodiment.

[0061] Such as figure 1 , figure 2 and image 3 As shown, this embodiment includes: a static pipeline with several input / output channels 1, 2, 3, 4;

[0062] A rotary device connected to the static pipeline, the rotary device includes: a plurality of rotary fluid channels for receiving or delivering fluid from the input and output channels respectively.

[0063] The static partition container 7 connected with the rotating device, the static partition container 7 includes: a static split area 8, a stationary phase filling area 9 and a peripheral fluid transfer area 10, between the units of each static split area 8, each The units in the stationary phase fi...

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PUM

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Abstract

Disclosed herein is a simulated moving bed for a chromatography device in the technical field of physical separation, comprising a stationary pipe with a plurality of inlet / outlet channels, a rotary device connected to the stationary pipe, a stationary segmented vessel that communicates with the rotary device, a fluid moving device to circulate the fluid, and a driver to rotate the rotary device for a fixed angle, wherein the one end of the rotational flow distribution channel of the rotary device communicates with the corresponding stationary inlet / outlet channel, and the other end communicates with the next corresponding stationary flow distribution segment of the stationary segmented vessel. The invention combines the advantages for radial flow and rotary valve, and the stationary phase filler and the fluid mobile phase can simulate relative motion by adding a fluid driving device and improving partition plates in different regions or communicating specific fluid transfer regions via pipes. The continuous chromatography is separated and changed to a simulated moving bed chromatography so as to enhance the stationary phase utilization and reduce the solvent consumption.

Description

technical field [0001] The invention relates to a device in the technical field of material separation, in particular to a simulated moving bed device for chromatography. Background technique [0002] When traditional chromatography separates material components, it uses batch processing, with samples flowing vertically through axial chromatographic columns. US Patent No. 2,985,589 discloses a continuous chromatography system using a simulated moving bed to achieve higher throughput with less solvent. Adsorption and desorption in this technology are carried out continuously, so that the output of extract and raffinate, the input of process feed and desorbent can be carried out simultaneously. The upward relative movement of the simulated adsorbent is simulated through the sequential downward movement of the inlet and outlet conduits of the process feed, extractant, desorbent and raffinate, and the junction points of the adsorption chamber. Fluid movement inside the adsorpt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D15/18
CPCG01N30/38B01J8/08G01N2030/386B01J2208/00876B01D15/1842B01J8/0214B01J2208/00814B01J8/0278G01N30/44
Inventor 阮立昂
Owner 阮立昂
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