Traditional Chinese medicinal composition for treating paradentitis, and formulation and preparation method thereof and toothpaste

A composition and periodontitis technology, applied in the field of traditional Chinese medicine, can solve the problems of unsatisfactory periodontitis curative effect, short drug action time, and many medication times, and achieve the effects of significant curative effect, no toxic side effects, and high cure rate.

Active Publication Date: 2012-10-03
文汉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide a novel traditional Chinese medicine composition for treating periodontitis and its preparation method, aiming at the unsatisfactory efficacy and inconvenient use of medicines for treating periodontitis in the current market and clinical practice , short drug action time, many times of medication, and drug resistance. On the basis of traditional medicine combined with many years of clinical experience, modern processing methods are adopted to carefully develop and obtain the traditional Chinese medicine composition of the present invention.

Method used

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  • Traditional Chinese medicinal composition for treating paradentitis, and formulation and preparation method thereof and toothpaste
  • Traditional Chinese medicinal composition for treating paradentitis, and formulation and preparation method thereof and toothpaste
  • Traditional Chinese medicinal composition for treating paradentitis, and formulation and preparation method thereof and toothpaste

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Effect test

preparation example Construction

[0070] When the dosage form of the Chinese medicine composition of the present invention is decoction, its preparation method comprises the following steps:

[0071] 1. The components are mixed in proportion, crushed and sieved into a powder of 100 mesh to 150 mesh;

[0072] 2. Add the powder obtained in step 1 into cold water and soak for 30 to 36 hours, decoct with a slow fire for 2 to 4 hours, filter the decoction to obtain the first filtrate, the quality of the added cold water It is 3 to 5 times the mass of the powder obtained in the first step;

[0073] 3. Add the filter residue obtained by filtering in the second step into cold water again, decoct with a slow fire for 2 hours to 4 hours, and filter to obtain the second filtrate. The quality of the added water is the same as that in the second step;

[0074] 4. Combine the two filtrates to obtain the decoction.

[0075] When the dosage form of the Chinese medicine composition of the present invention is tablet, its pre...

Embodiment 1

[0099] The toxicity test of embodiment 1 Chinese medicine composition of the present invention

[0100] 1. Acute toxicity:

[0101] Test drug:

[0102] Mix 50g Astragalus membranaceus, 22g Atractylodes macrocephala, 18g Pearl ginseng, 16g Adenophora, 25g Polygonatum, 35g wolfberry, 40g donkey-hide gelatin, 15g tortoise shell, 20g gypsum, 17g light bamboo leaves, 14g salvia, 13g poria and 12g licorice, crush and sieve Make powder of 100 mesh to 150 mesh; add the obtained powder to 1200g cold water and soak for 36 hours, decoct with slow fire for 4 hours, filter the decoction to obtain the first filtrate; add the filter residue obtained by filtration to 1200g decocting in cold water for 4 hours, and filtering to obtain the second filtrate; combining the two filtrates to obtain the decoction.

[0103] Experimental procedure:

[0104] Get 40 ICR mice (provided by Beijing Weitong Lihua Experimental Animal Technology Co., Ltd.), with a body weight of 25 to 30 grams, and administe...

Embodiment 2

[0110] The preparation of the decoction of embodiment 2 Chinese medicine composition of the present invention

[0111] Mix 50g Astragalus membranaceus, 22g Atractylodes macrocephala, 18g Pearl ginseng, 16g Adenophora, 25g Polygonatum, 35g wolfberry, 40g donkey-hide gelatin, 15g tortoise shell, 20g gypsum, 17g light bamboo leaves, 14g salvia, 13g poria and 12g licorice, crush and sieve Make powder of 100 mesh to 150 mesh; add the obtained powder to 1200g cold water and soak for 36 hours, decoct with slow fire for 4 hours, filter the decoction to obtain the first filtrate; add the filter residue obtained by filtration to 1200g decocting in cold water for 4 hours, and filtering to obtain the second filtrate; combining the two filtrates to obtain the decoction.

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Abstract

The invention provides a traditional Chinese medicinal composition for treating paradentitis. The traditional Chinese medicinal composition comprises milkvetch root, bighead atractylodes rhizome, rhizoma panacis majoris, coastal glehnia root, solomonseal rhizome, Chinese wolfberry fruit, donkey-hide glue, tortoise shell, gypsum, lophatherum gracile, root of red-rooted salvia, indian bread and liquorice root. The traditional Chinese medicinal composition is therapeutically effective for treating the paradentitis of patients, free of any toxic or side effect and phytotoxicity, and low in cost, and can treat both manifestation and root cause of the paradentitis, strengthen body resistance to eliminate pathogenic factors, comprehensively regulate the body and balance yin and yang. Furthermore, by the aid of the traditional Chinese medicinal composition, the paradentitis is not prone to relapse.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating periodontitis. Background technique [0002] Periodontitis is a clinically common and frequently-occurring disease, caused by systemic factors and local factors, which can cause heel inflammation, periodontal pocket formation, alveolar bone resorption and tooth loosening, and eventually lead to tooth loss. The pathogenesis has not been elucidated. According to the survey data of the World Health Organization (WHO), the prevalence rate of periodontal disease is as high as 75%, and in some areas of my country, it can be as high as 93%. It is one of the main reasons for the loss of teeth in adults in my country. In addition, periodontitis is also a potential risk factor for certain systemic diseases, such as diabetes, respiratory diseases, rheumatoid arthritis, cardiovascular diseases, and the induction o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K8/98A61K8/97A61K9/20A61K9/12A61P1/02A61Q11/00A61K8/23A61K33/06A61K35/36A61K35/56A61K35/586
Inventor 刘霞
Owner 文汉
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