A traditional Chinese medicine composition for treating brain injury and cerebral edema and its application

Abstract

The invention relates to a traditional Chinese medicinal extract product prepared from traditional Chinese medicinal raw materials composed of root of large-flowered skullcap, cape jasmine and pseudo-ginseng, a traditional Chinese medicinal composition containing scutelloside, geniposide and panax notoginseng saponins, a medicine containing the traditional Chinese medicinal extract product or the traditional Chinese medicinal composition, and their clinical application. The traditional Chinese medicinal extract product, the traditional Chinese medicinal composition and the medicine containing the traditional Chinese medicinal extract product or the traditional Chinese medicinal composition can be used in emergency treatment and treatment of diseases such as cerebrovascular disease, intracranial infection, craniocerebral trauma, craniocerebral space-occupying lesion or intoxication and the like, which are mainly represented by brain edema.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating brain injury and cerebral edema, which is composed of Scutellaria baicalensis, Gardenia jasmine and Panax notoginseng. It is characterized by the occurrence or imminent occurrence of an inflammatory response in the central nervous system. Background technique [0002] Cerebral edema refers to the pathological phenomenon that the increase of water in the brain leads to the increase of brain volume, and it is the response of brain tissue to various pathogenic factors. Clinically, it is common in nervous system diseases, such as cerebrovascular diseases, intracranial infections (encephalitis, meningitis, etc.), craniocerebral trauma, intracranial space-occupying diseases (such as tumors), seizures, and systemic diseases such as toxic dysentery , Severe pneumonia. Cerebral edema can be divided into four categories according to pathological morphology and pathogenesis: (1) va...

AI Technical Summary

Problems solved by technology

However, the above-mentioned treatments are all symptomatic treatments, and do not target the pathogenesis of brain injury and / or cerebral edema, and their application has certain limitations

However, long-term use of high-dose glucocorticoids will cause a series of metabolic disorders of sugar, protein, fat, water and electrolytes, damage the body's defense system and suppress immune response, and cause various complications, some of which may directly threaten the lives of patients ; Large doses of rapid intravenous infusion of mannitol can cause water and electrolyte disorders, leading to heart failure, or cause various central nervous system symptoms due to tissue dehydration; the application of diuretics can also cause adverse reactions such as water and electrolyte disorders; traditional Chinese medicine preparations are mostly Oral preparations are limited in the first aid of cerebral edema and brain injury, and the existing traditional Chinese medicine injections are not aimed at the inflammatory immune mechanism of cerebral edema and brain injury, and there are many side effects

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