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Preparation method of traditional Chinese medicine plastic for treating bovine mastitis

The technology of film coating agent and traditional Chinese medicine is applied in the field of preparation of traditional Chinese medicine film coating agent for treating dairy cow mastitis, which can solve problems such as drug health hazards, and achieve the effects of easy operation, good therapeutic effect and remarkable clinical effect.

Inactive Publication Date: 2013-12-04
NINGXIA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the clinical treatment of mastitis in dairy cows is mainly based on the prevention and treatment of antibiotics. The long-term use of antibiotics in large quantities not only leads to the emergence of drug-resistant strains, but also the residues of drugs will also cause harm to human health.

Method used

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  • Preparation method of traditional Chinese medicine plastic for treating bovine mastitis
  • Preparation method of traditional Chinese medicine plastic for treating bovine mastitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 1. Extraction of effective components of traditional Chinese medicine: In the following extraction methods, 1 part is equivalent to 50g of traditional Chinese medicine, 1:1 liquid extract, that is, 1g of medicinal materials will finally obtain 1ml of liquid extract.

[0029] ① Extraction of raw rhubarb:

[0030] First, the raw rhubarb is crushed to 40 meshes, then 1 part of the crushed raw rhubarb is put into an ethanol solution with 8 times the weight of the medicinal material and a volume concentration of 90%, and the method of (hot) reflux is used to extract twice, the first time The extraction time is 2 hours, the second extraction time is 1 hour, and the extraction temperature is 80°C. After the two extracts are mixed and filtered with a single layer of filter paper, the filtrate is concentrated on a rotary evaporator to make a 1:1 ratio. Fluid extract is 50ml;

[0031] ②Extraction of honeysuckle vines: first crush the honeysuckle vines to 40 mesh, then put 2 part...

Embodiment 2

[0049] 1. Extraction of active ingredients of traditional Chinese medicine:

[0050] (1) Water decoction:

[0051] Chinese medicine name

number of copies

solid to liquid ratio

Extraction times

extraction time

honeysuckle vine

2

1∶10

3

60

dandelion

2

1∶20

3

90

angelica

1

1∶10

3

60

Curcuma

2

1∶10

3

30

frankincense

2

1∶10

3

30

[0052] myrrh

2

1∶10

3

30

[0053] (2) Reflux extraction:

[0054]

[0055] (3) Ultrasonic extraction:

[0056]

[0057] 2. Compatibility of traditional Chinese medicine

[0058] Prepare 800ml of traditional Chinese medicine compound according to the above method, after standing at room temperature for 24h, then centrifuge at 3000r / min for 30min, collect the supernatant, discard the residue, and concentrate the supernatant to 1.5 ...

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Abstract

The invention relates to a preparation method of a traditional Chinese medicine plastic for treating bovine mastitis. The method is characterized by adopting the raw materials including rheum officinale, Chinese angelica, garden balsam stem, caulis lonicerae, herba taraxaci, rhizoma curcumae, frankincense, myrrh, flos lonicerae, herba violae and fructus forsythia and comprising the following steps of: separately extracting the raw materials and concentrating into liquid extract, and compounding and compatibilizing to obtain the finished traditional Chinese medicine; and mixing the traditional Chinese medicine with a plastic matrix and a transdermal agent to obtain the traditional Chinese medicine plastic. According to experiment statistics, the cure rates of the traditional Chinese medicine plastic provided by the invention on clinical and recessive mastitis are 72% and 85.3% respectively, a good therapeutic effect is realized, and the clinical symptoms of the case which is not cured are obviously eased. Moreover, the traditional Chinese medicine plastic is a pure traditional Chinese medicine preparation, has the advantages of bacteria resistance, inflammation diminishment, no residue and the like, and is easy to prepare and operate; and the clinical effect is obvious and better than that of the existing ointment.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine coating agent for treating cow mastitis. Background technique [0002] Cow mastitis (Mastitis), also known as milk yellow, milk swelling and milk carbuncle in traditional Chinese veterinary medicine, is a complex mammary gland syndrome, which is an inflammatory reaction caused by the damage of dairy cow udders by harmful factors such as microorganisms, physics and chemistry. , which is characterized by various types of inflammation of the mammary gland, manifested as mammary gland infection, mammary gland inflammation, breast microcirculation and immune disorders, etc.; at the same time, the physical and chemical properties and bacteriological changes of milk occur, and it is divided into clinical mastitis and recessive mastitis There are two types of mastitis. Pathogenic microorganisms are mainly Escherichia coli, Staphylococcus aureus and Streptococcus. [0003] Mastiti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/70A61P15/14
Inventor 何生虎蒋魏娟郭磊付少刚李勇
Owner NINGXIA UNIVERSITY
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