The invention belongs to the field of biotechnologies of dairy cow veterinary drugs, and particularly relates to a Chinese and western medicine compound for preventing and treating recessive mastitis of dairy cows. The compound is prepared from the following Chinese and western medicinal materials by weight: 10-15g of levamisole hydrochloride, 25-30g of taurine, 55-60g of honeysuckle, 45-50g of angelica sinensis, 25-30g of orange peel, 15-20g of radix saposhnikoviae, 15-20g of radix angelicae, 20-25g of fritillaria thun-bergli, 20-25g of frankincense, 20-25g of myrrh, 25-30g of radix paeoniae rubra, 15-20g of manis pentadactyla and 10-15g of liquorice. The Chinese and western medicine compound for preventing and treating recessive mastitis of dairy cows is prepared on the basis of years of clinical experience, has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis and eliminating swelling to promote lactation, and has the advantages of being residue-free, pollution-free, environment-friendly, safe, simple in production process and convenient to use.