Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

An antibacterial feed additive and its application

A feed additive and feed technology, which is applied in the field of animal husbandry or feed, can solve the problems such as application reports of antibacterial feed additives with no antibacterial effect of glycerol lactate, and achieve the effects of improving feed conversion efficiency, avoiding acid corrosion damage, and promoting animal growth.

Active Publication Date: 2017-05-10
HUBEI HAOHUA BIOTECH
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no report on the antibacterial effect of glyceryl lactate and its application as an antibacterial feed additive.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • An antibacterial feed additive and its application
  • An antibacterial feed additive and its application
  • An antibacterial feed additive and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] According to the orthogonal test design table L9 (3 4 ) Arrange the combination (see test numbers 4 to 12 in Table 1), and use the Oxford cup method to determine the antibacterial activity of single substances of mono-, di- and tri-glycerides and their combinations.

[0019] Table 1 Antibacterial effect of glycerol lactate in vitro

[0020]

[0021] Note: The numbers in the table indicate the mass ratio of mono-glycerides, di-glycerides and tri-glycerides in combination.

[0022] The data in Table 1 shows that monolactate, dilactyl, and trilactate and their mixtures in different proportions have inhibitory effects on E. coli and Salmonella, and the size of the in vitro inhibition zone is 14.33-19.33mm and 12.00, respectively. ~ 16.10mm.

Embodiment 2

[0024] The glycerol monolactate, glycerol dilactide, and glycerol trilactate are 1:0:0, 0:1:0, 0:0:1, 1:0:2, 0:1:3 and 3 in mass ratios. :1:3 is fully mixed with liquid mixing equipment to prepare glycerol lactate mixture I, II, III, IV, V, VI. Then, the glycerol lactate mixture and defatted rice bran are thoroughly mixed according to a weight ratio of 1:1 to form the antibacterial feed additive of the present invention. The additive is added at 1.0% of the weight of the feed (the actual feed contains 0.5% of glycerol lactate).

[0025] The formula of this example is suitable for weaning piglets, and the application effect is obvious.

[0026] Feed the weaned piglets with this additive. A total of 168 21-day-old weaned piglets with the same weight and sex were randomly divided into 7 groups, each group had 3 replicates (columns), and each group had 8 piglets. The basal diets fed by the experimental groups were the same. Experiments Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ and Ⅵ were fed with 1.0% antibac...

Embodiment 3

[0032] The glycerol monolactate, glycerol dilactide, and glycerol trilactate are 1:0:0, 0:1:0, 0:0:1, 2:1:0, 1:2:3 and 3 according to the mass ratio. :2:1 Fully mixed with liquid mixing equipment to prepare glycerol lactate mixture I, II, III, IV, V, VI. Then, the glycerol lactate mixture and the silicon dioxide are fully mixed according to the weight ratio of 1:1 to form the antibacterial feed additive of the present invention. The additive is added at 0.02% of the weight of the feed (the actual feed contains 0.01% of glycerol lactate).

[0033] The formula of this example is suitable for broilers, and the application effect is obvious.

[0034] Feed the Cobb broilers with this additive. 560 1-day-old Cobb broilers (half male and half male) with the same body weight were randomly divided into 7 groups with 8 replicates (cages) in each group, 10 per cage. The basal rations for all groups were the same. Experiments I, II, III IV, V, VI groups were fed with 0.02% antibacterial fe...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an antibacterial feed additive which comprises an effective component, namely, monolactic acid glyceride, dilactic acid glyceride, trilactic acid glyceride or a mixture of two or three of monolactic acid glyceride, dilactic acid glyceride and trilactic acid glyceride in any ratio. A use method of the antibacterial feed additive is that the antibacterial feed additive which accounts for 0.01-0.5% of the total weight of feed is directly added into livestock and aquatic livestock feed, or the antibacterial feed additive is mixed with a carrier to prepare a premix, or the antibacterial feed additive is mixed with other feed additives or feed raw materials to prepare a premix and concentrated materials to feed livestock and aquatic livestock. The antibacterial feed additive has the outstanding advantages that due to addition of the lactic acid glyceride, the additive has the advantages of high security and no medicine resistance, can effectively replace feed antibiotics, and meets the healthful aquaculture development direction. The additive can inhibit the repruduction of intestinal harmful microorganisms of animals, promote animal growth, improve the feed conversion efficiency and reduce the disease rate.

Description

Technical field [0001] The invention belongs to the technical field of animal husbandry or feed, and relates to an antibacterial feed additive. Background technique [0002] While the application and promotion of feed antibiotics promotes the rapid development of the aquaculture industry, it also brings a series of negative effects. The long-term excessive use of antibiotics has led to the emergence of a large number of drug-resistant strains, and antibiotics remain in meat products, seriously endangering human and animal health. Antibiotic residues can cause human acute toxicity, allergic reactions and allergies, carcinogenic, teratogenic and mutagenic effects, and disrupt the normal microecological balance of the gastrointestinal tract; due to the increase in bacterial resistance, the drug resistance genes of animal pathogens will also be transmitted to humans Pathogens, which in turn pose a huge threat to human health. [0003] my country is a country where feed antibiotics ar...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A23K20/158
Inventor 侯永清丁斌鹰
Owner HUBEI HAOHUA BIOTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com