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Antibacterial feed additive and application

A feed additive and feed technology, applied in the field of animal husbandry or feed, can solve the problems such as no reports on the application of antibacterial feed additives with the antibacterial effect of glycerol lactate, and achieve the effects of improving feed conversion efficiency, reducing disease incidence, and promoting animal growth.

Active Publication Date: 2015-01-28
HUBEI HAOHUA BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no report on the antibacterial effect of glyceryl lactate and its application as an antibacterial feed additive.

Method used

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  • Antibacterial feed additive and application
  • Antibacterial feed additive and application
  • Antibacterial feed additive and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Glyceryl monolactate, glyceryl dilactate and glyceryl trilactate were determined according to the orthogonal experiment design Table L9 (3 4 ) to arrange combinations (see test numbers 4 to 12 in Table 1), and use the Oxford cup method to measure the antibacterial activity of a single substance of monolactyl glyceride, dilactyl glyceride and trilactyl glyceride and the composition thereof.

[0019] Table 1 Antibacterial effect of glyceryl lactate in vitro

[0020]

[0021] Note: The figures in the table represent the mass ratio of monolactyl glyceride, diglyactin glyceride and trilactyl glyceride when used in combination.

[0022] The data in Table 1 show that glycerol monolactate, glyceryl digactate and glyceryl trilactate and their mixtures in different proportions have inhibitory effects on Escherichia coli and Salmonella. ~16.10mm.

Embodiment 2

[0024] Glyceryl monolactate, glyceryl dilactate and glyceryl trilactate are in the mass ratio of 1:0:0, 0:1:0, 0:0:1, 1:0:2, 0:1:3 and 3 : 1:3 Lactate glyceride mixture Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ, Ⅵ is prepared by fully mixing with liquid mixing equipment. Then, the glycerol lactate mixture and the defatted rice bran are fully mixed according to the weight ratio of 1:1 to form the antibacterial feed additive of the present invention. The additive is added according to 1.0% of the weight of the feed (the actual feed contains 0.5% of glyceryl lactate).

[0025] The formula in this example is suitable for weaned piglets, and the application effect is obvious.

[0026] Feed weaned piglets with this example additive. 168 21-day-old weaned piglets with the same body weight and gender were randomly divided into 7 groups, each group had 3 replicates (columns), and each pen had 8 piglets. The basal diet fed to each experimental group was the same. Experiments Ⅰ, Ⅱ, ⅢⅣ, Ⅴ, Ⅵ groups were fed with...

Embodiment 3

[0032] Glyceryl monolactate, glyceryl dilactate and glyceryl trilactate are in the mass ratio of 1:0:0, 0:1:0, 0:0:1, 2:1:0, 1:2:3 and 3 : 2:1 Lactate glyceride mixture Ⅰ, Ⅱ, Ⅲ, Ⅳ, Ⅴ, Ⅵ is prepared by fully mixing with liquid mixing equipment. Then, the glycerol lactate mixture and silicon dioxide are fully mixed according to the weight ratio of 1:1 to form the antibacterial feed additive of the present invention. The additive is added according to 0.02% of the weight of the feed (the actual feed contains 0.01% of glyceryl lactate).

[0033] The formula in this example is suitable for broiler chickens, and the application effect is obvious.

[0034] Cobb broiler chickens were fed with the supplement of this example. 560 1-day-old Cobb broilers (half male and half female) with basically the same body weight were randomly divided into 7 groups, each group had 8 replicates (cages), and each cage had 10 broilers. Each group was fed with the same basal diet. Experiment Ⅰ, Ⅱ, ⅢⅣ...

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Abstract

The invention discloses an antibacterial feed additive which comprises an effective component, namely, monolactic acid glyceride, dilactic acid glyceride, trilactic acid glyceride or a mixture of two or three of monolactic acid glyceride, dilactic acid glyceride and trilactic acid glyceride in any ratio. A use method of the antibacterial feed additive is that the antibacterial feed additive which accounts for 0.01-0.5% of the total weight of feed is directly added into livestock and aquatic livestock feed, or the antibacterial feed additive is mixed with a carrier to prepare a premix, or the antibacterial feed additive is mixed with other feed additives or feed raw materials to prepare a premix and concentrated materials to feed livestock and aquatic livestock. The antibacterial feed additive has the outstanding advantages that due to addition of the lactic acid glyceride, the additive has the advantages of high security and no medicine resistance, can effectively replace feed antibiotics, and meets the healthful aquaculture development direction. The additive can inhibit the repruduction of intestinal harmful microorganisms of animals, promote animal growth, improve the feed conversion efficiency and reduce the disease rate.

Description

technical field [0001] The invention belongs to the technical field of animal husbandry or feed, and relates to an antibacterial feed additive. Background technique [0002] The application and promotion of feed antibiotics has brought a series of negative effects while promoting the rapid development of the aquaculture industry. The long-term overuse of antibiotics has led to the emergence of a large number of drug-resistant strains, and the residues of antibiotics in meat products have seriously endangered the health of humans and animals. Antibiotic residues can lead to acute toxicity in humans, allergic reactions and allergic reactions, carcinogenic, teratogenic and mutagenic effects, and damage to the normal micro-ecological balance of the gastrointestinal tract, etc.; due to the increase in bacterial resistance, the drug resistance genes of animal pathogens will also be transmitted to humans Pathogens pose a huge threat to human health. [0003] my country is a count...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/16
Inventor 侯永清丁斌鹰
Owner HUBEI HAOHUA BIOTECH
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