New dual-chamber transfusion bag for packaging amino acid and glucose injection

A technology for infusion bags and injections, applied in the field of medicine, can solve problems such as lack of mixing conditions, increased pollution, cumbersome preparation process, etc., and achieve the effect of reducing the risk of pollution

Inactive Publication Date: 2012-10-31
LIAONING HAISCO PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The current total parenteral nutrition infusion generally pours different types of infusion into a large mixed bag. Generally, there are operating rooms in tertiary hospitals, which can reduce the chance of contamination, but cannot completely guarante

Method used

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  • New dual-chamber transfusion bag for packaging amino acid and glucose injection
  • New dual-chamber transfusion bag for packaging amino acid and glucose injection
  • New dual-chamber transfusion bag for packaging amino acid and glucose injection

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0032] The preparation process of the double-chamber infusion bag of the present invention

[0033]

[0034]

[0035]

[0036] *: In the three-layer co-extrusion film for infusion, the outer film is composed of polypropylene, styrene-ethylene-butylene copolymer; the middle film is composed of polypropylene / polyethylene, styrene-ethylene-butylene copolymer; the inner film is composed of polypropylene / polyethylene and styrene-ethylene-butylene copolymer; The layer film consists of polypropylene, styrene-ethylene-butylene copolymer.

[0037] **: The three-layer co-extrusion film for infusion is derived from the three-layer co-extrusion film for infusion of PolyCineGmbH (registration certificate number: J20060015).

Example Embodiment

[0038] Experimental Example 1 - Appearance Detection

[0039] Take 10 each of Examples 1 to 32 of the present invention, and look at them in a bright place with natural light, and they are all transparent, smooth, and free of foreign objects visible to the naked eye. There are no cracks, fissures, pores, colored embedded objects and foreign body deposits at the mouth tube interface.

Example Embodiment

[0040] Experimental Example 2 - Identification

[0041] (1) Microscopic features: Take 10 of each of Examples 1-32 of the present invention, cut them into appropriate thicknesses, and observe them under a microscope. The cross-section shows three clear layers.

[0042] (2) Welding strength: Take Examples 1-32 of the present invention and measure them according to the method of composite bag in the heat sealing strength determination method (YBB00122003), and the average value of each heat sealing part is not less than 25N / 15mm.

[0043] (3) Welding strength: Take Examples 1-32 of the present invention and measure them according to the method of composite bag in the heat sealing strength determination method (YBB00122003). The average value of each heat sealing part is (5N-20N) / 15mm.

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Abstract

The invention belongs to the technical field of medicines, and in particular relates to a triple-layer co-extrusion dual-chamber transfusion bag. The dual-chamber transfusion bag is prepared by heat seal; a peelable separate is formed by cold solder joint between two chambers through a special hot press method, the separate plays a role in separating liquid medicines in the two chambers when the liquid medicines are stored and transferred, and the separate can be conveniently opened by applying a certain pressure, so that the two chambers are communicated, and the liquid medicines in the two chambers are mixed. According to the dual-chamber transfusion bag, mixing misoperation which easily occurs when general infusions are mixed can be avoided, particles generated by puncture and cross infection in mixing and the like can be reduced, the transfusion stability can be improved, and the infusion packaged by the dual-chamber bag is in accordance with the requirement of safe, quick and convenient transfusion treatment clinically.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a three-layer co-extruded double-chamber infusion bag for packaging amino acid glucose injection. Background technique [0002] Since the introduction of intravenous infusion in 1931, infusion therapy has become one of the most common and common clinical treatments. The packaging form of infusion solution has mainly gone through the following stages in the development: glass bottle infusion solution - plastic bottle infusion solution - PVC soft bag infusion solution - non-PVC soft bag infusion solution. The three-layer co-extruded double-chamber infusion bag is what is commonly referred to as a ready-to-use soft infusion bag. [0003] In order to ensure the tightness of the solder joints during sterilization and storage and transportation, and to be able to open them conveniently during use, the requirements for packaging materials, production equipment and processe...

Claims

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Application Information

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IPC IPC(8): A61J1/10
Inventor 佐建锋冯卫张晓琳
Owner LIAONING HAISCO PHARMACEUTICAL CO LTD
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