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Compound bactericide containing natamycin and uses of same

A technology for compounding fungicides and containing natamycin, applied in the directions of fungicides, biocides, biocides, etc., can solve the problems of threatening the health of consumers, increasing the use of drugs, and pathogenic bacteria resistance. Easy to drug resistance, easy to use, effect of drug resistance

Active Publication Date: 2012-12-05
陕西百姓堂制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

All 3 postharvest fungicides face the same problem: pathogen resistance
Once the pathogenic bacteria have serious drug resistance to the medicament, on the one hand, it will bring about a significant decline in the control effect in production, and even some diseases will not be available; Residual toxicity problem, a serious threat to the health of consumers

Method used

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  • Compound bactericide containing natamycin and uses of same
  • Compound bactericide containing natamycin and uses of same
  • Compound bactericide containing natamycin and uses of same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1, indoor formula screening:

[0031] Toxicity and synergistic coefficients were determined by dissolving natamycin and imazalil in different weight ratios in methanol, using the mycelial growth method to measure the inhibitory effect on Penicillium citri (Table 1), and then calculating EC 50 value and synergy factor.

[0032] According to the main prevention and control objects, select the ratio of synergistic coefficient (SR) ≥ 1.5, and carry out appropriate dosage form processing.

[0033] Table 1, the formula screening of preventing and treating Penicillium citrus

[0034]

[0035]Note: the above parentheses refer to the weight ratio of the two components, and the Penicillium citrus bacteria used in the experiment are resistant to imazalil.

Embodiment 2

[0036] Embodiment 2, indoor formula screening:

[0037] Toxicity and synergistic coefficient are determined by dissolving natamycin and carbendazim in different weight ratios respectively in hydrochloric acid solutions with a concentration of 0.1N, and using the mycelium growth method to determine the effect on Gibberella tritici (Table 2 ) inhibition, and then calculate the EC 50 value and synergy factor.

[0038] Table 2. Formula screening for preventing and treating wheat diseases

[0039]

[0040] Note: The above brackets refer to the weight ratio of the two components, and the experimental Fusarium rubella is resistant to carbendazim.

Embodiment 3

[0041] Embodiment 3, indoor formula screening:

[0042] Toxicity and synergistic coefficients were determined by dissolving natamycin and prochloraz in methanol at different weight ratios, using the mycelium growth method to measure the inhibitory effect on rice bakanae pathogen (Table 3), and then calculating EC 50 value and synergy factor.

[0043] According to the main prevention and control objects, select the ratio of synergistic coefficient (SR) ≥ 1.5, and carry out appropriate dosage form processing.

[0044] Table 3. Formula screening for controlling rice bakanae disease

[0045]

[0046] Note: The above parentheses refer to the weight ratio of the two components, and the bakanae pathogen used in the experiment is resistant to prochloraz.

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PUM

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Abstract

The invention discloses a compound bactericide containing natamycin, which comprises components with weight fractions as follows: 10 percent to 90 percent of components A and 90 percent to 10 percent of components B, wherein the components A are natamycin and the components B are carbendazim, imazalil or prochloraz; and the compound bactericide can be prepared into an emulsion type bactericide or a power / grain type bactericide. The compound bactericide is used for preventing and curing storage period diseases of fruits during postharvest treatment or used for preventing and curing growing period diseases of crops, wherein the storage period diseases of the fruits mainly refer to citrus blue mold or citrus green mold, and the growing period diseases of the crops mainly refer to wheat scabs or rice bakanae diseases.

Description

technical field [0001] The invention relates to a fungicide, in particular to a green storage and antistaling agent used for preventing and treating diseases of fruits and grain crops-a compound fungicide containing natamycin and its application. Background technique [0002] Plant diseases in our traditional understanding basically refer to diseases that occur during the growth of plants, referred to as mid-birth diseases for short, and a lot of attention has been paid to such diseases. The vast majority of research is also aimed at these diseases, and the disease control products on the market are basically aimed at them. However, little attention has been paid to diseases that occur during storage and transportation after plant harvest (referred to as postharvest diseases), and there are even fewer effective control products. Taking citrus penicillium and citrus green mold as examples, they are caused by Penicillium italicum and Penicillium digitatum respectively, which ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N47/38A01N47/18A01N43/90A01N43/50A01P3/00
Inventor 张传清朱祝军吴慧明
Owner 陕西百姓堂制药有限公司
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