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Traditional Chinese medicine composition used for preventing and treating mixed infection of poultry coccidiosis and necrotic enteritis

A technology for necrotic enteritis and poultry coccidiosis, applied in the direction of anti-infective drugs, drug combinations, antibacterial drugs, etc. It is difficult for drugs to achieve satisfactory curative effect, and it is difficult to effectively control disease rebound and other problems, so as to achieve the effect of reducing drug residues, low cost, and reduced use

Inactive Publication Date: 2013-10-30
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] ①The reported traditional Chinese medicine prescriptions mainly focus on the principles of insecticide and deworming in principle, without considering the synergy between the onset of coccidiosis and necrotic enteritis, so it is difficult to effectively control the rebound of the disease after treatment
②Because the clinical symptoms of coccidiosis and necrotic enteritis are highly similar, and there is a high probability of secondary circulation between the two, it is difficult to achieve satisfactory curative effect with a single anticoccidiosis drug or antibacterial drug
③ Commonly used anti-coccidial and antibacterial western medicine preparations often have inaccurate curative effects due to the emergence of drug resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment one: the preparation of Chinese medicine powder

[0024] The traditional Chinese medicine composition consists of 30 parts of thistle, 50 parts of Artemisia annua, 15 parts of Astragalus, 30 parts of Atractylodes macrocephala and 10 parts of licorice. The various flavors of traditional Chinese medicines are decoction pieces of traditional Chinese medicines conforming to the relevant standards of "Chinese Veterinary Pharmacopoeia", and all proportions are parts by weight. Mix and pulverize the traditional Chinese medicines, pass through a 60-mesh rotary vibrating sieve, pulverize the coarser Chinese medicine particles again, mix the Chinese medicine fine powder, and pack into 1kg / bag to obtain. The traditional Chinese medicine powder produced by this method is generally used for the prevention and treatment of poultry coccidiosis and necrotic enteritis such as broilers and laying hens by feeding with mixing materials. When used for treatment, the powder can al...

Embodiment 2

[0025] Embodiment two: the preparation of Chinese medicine oral liquid

[0026] The traditional Chinese medicine composition is composed of 60 parts of thistle, 30 parts of Artemisia annua, 30 parts of Astragalus, 15 parts of Atractylodes macrocephala and 25 parts of licorice. The various flavors of traditional Chinese medicines are decoction pieces of traditional Chinese medicines conforming to the relevant standards of "Chinese Veterinary Pharmacopoeia", and all proportions are parts by weight. Add 10 times the amount (weight ratio) of each traditional Chinese medicine to soak in purified water for 5 hours, heat it to boiling, and keep it warm for 1 hour. hours, filter, combine two filtrates, heat and concentrate until the crude drug ratio is 0.5kg / L, add ethanol to 75% (volume ratio), precipitate for 12 hours, heat the supernatant to recover ethanol, and concentrate the medicinal solution until the crude drug ratio is 1kg / L, add 0.3% sodium benzoate for anticorrosion, fill...

Embodiment 3

[0027] Embodiment three: the preparation of Chinese medicine granule

[0028] The traditional Chinese medicine composition is composed of 50 parts of thistle, 40 parts of Artemisia annua, 25 parts of Astragalus, 25 parts of Atractylodes macrocephala and 20 parts of licorice. The various flavors of traditional Chinese medicines are decoction pieces of traditional Chinese medicines conforming to the relevant standards of "Chinese Veterinary Pharmacopoeia", and all proportions are parts by weight. Add 10 times the amount (weight ratio) of each traditional Chinese medicine to soak in purified water for 2 hours, heat to boiling, and keep warm for 1 hour. hours, filter, combine two filtrates, heat and concentrate until the crude drug ratio is 0.5kg / L, add ethanol to 75% (volume ratio), precipitate for 12 hours, heat the supernatant to recover ethanol, and concentrate the medicinal solution until the crude drug ratio is 5kg / L, add appropriate amount of sucrose or glucose, granulate,...

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PUM

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Abstract

The invention relates to traditional Chinese medicine composition used for preventing and treating mixed infection of poultry coccidiosis and necrotic enteritis. The traditional Chinese medicine composition takes common cephalanoplos herb used for cooling blood and hemostasis, removing stasis and dispersing swellings as monarch drug, and takes sweet wormwood herb used for clearing deficiency-heat, cooling blood and removing steam as minister drug. Moreover, the traditional Chinese medicine composition is additionally provided with astragalus used for tonifying qi, strengthening exterior, eliminating sores and promoting granulation, and white atractylodes rhizome used for invigorating spleen, supplementing qi, eliminating dampness, and alleviating water retention as the assistant drug and liquorice used for tonifying spleen and qi and clearing away heat and toxic materials is used for coordinating the drugs. The traditional Chinese medicine composition has the functions of cooling blood, removing stasis, clearing heat and toxic materials, and consolidating basis of the human body, and can meets the prevention and cure requirements of different paroxysm stages of the mixed infection of poultry coccidiosis and necrotic enteritis. The clinical application of a large amount of poultry diseases proves that the traditional Chinese medicine composition has the advantages of precise effects, no toxic and side effects, no drug residue and the like.

Description

[0001] A composition of Chinese traditional medicine preventing polyinfection of cidiosis and Necrotic Enteritis of poultry technical field [0002] The invention belongs to the field of production and application of veterinary medicine preparations, relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for preventing and treating poultry coccidiosis and necrotic enteritis mixed infection. Background technique [0003] Coccidiosis is currently the most serious and most common protozoan disease that harms the poultry industry. It has been found in clinical practice that most cases of coccidiosis infection often form mixed infections with necrotic enteritis. In terms of pathogenesis, when coccidia infection occurs, the integrity of the intestinal mucosa is damaged and the barrier function is lost, which opens the door for the invasion of intestinal pathogenic bacteria such as Clostridium perfringens and Clostridium ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/484A61P33/02A61P31/04A61P1/00
Inventor 刘宗柱李斐
Owner QINGDAO AGRI UNIV