Glucose sensor

Abstract

The invention discloses a glucose sensor, which comprises a counter electrode and at least one working electrode, wherein the counter electrode and the working electrode are fixedly arranged on a base; and a degradable layer is coated on the outermost layer of the at least one working electrode. By coating the degradable layer on the surface of the working electrode of the sensor, a relay mechanism of sequential enzyme release can be formed, the service life of the sensor can be obviously prolonged compared with the conventional service life of 3-5 days, and the correction frequency of the sensor is reduced compared with that of the conventional sensor. The sensor has the advantages of small size, relatively simple manufacturing process and low manufacturing cost. Since the service life of the sensor is prolonged, a patient needs not to frequently replace the sensor, and the economic burden of the patient is also obviously reduced. The implanted or intrusive real-time detection glucose sensor with long service life and good biocompatibility has broad application prospect in implanted or intrusive medical detection equipment.

Description

technical field [0001] The invention relates to a glucose sensor and belongs to the field of medical detection equipment. Background technique [0002] Diabetes is a serious threat to human health. Diabetics need to adjust their diet by measuring the blood glucose concentration several times a day to achieve the purpose of controlling blood sugar. The traditional blood glucose monitoring method is the fingertip blood sampling method. The detection result of this method is accurate, but the patients often feel discomfort and fear, and the number of detections per day is limited, which cannot fully reflect the patient's blood glucose changes in real time, so it cannot provide enough valuable information. Treatment basis, and continuous detection data information can provide fundamental improvements for the diagnosis and treatment of diabetes. [0003] The subcutaneous implantable real-time blood glucose monitoring system implants the sensor probe under the skin, which can con...

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Problems solved by technology

[0006] Chinese patent document CN101530327A aims at the poor biocompatibility of the glucose sensor in the prior art, which cannot provide the user with the current blood glucose level in real time, and provides a needle-shaped amperometric glucose sensor with good biocompatibility for real-time monitoring of subcutaneous tissue The working electrode of the sensor has a conductive layer, an inner film layer of a polymer material, an enzyme film layer and a control diffusion layer of a polymer material and is formed by sequentially covering from the inside to the outside.

[0007] From the above analysis, it can be seen that the service life of the existing subcutaneous implantable real-time blood glucose detection sensor is too short, and the patient needs to change the monitoring probe frequently, which is not very convenient to use, and the price of the existing probe on the market is about tens of yuan , frequent replacement will sharply increase the economic burden on patients

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