Bactericidal composition containing prothioconazole and trifloxystrobin

A technology of prothioconazole and trifloxystrobin, applied in the field of pesticides, can solve the problems of unpredictable synergistic effect, unpredictable and difficult environmental impact and effect, difficult industrialization of pharmaceutical compositions, etc. Medicinal properties, improved control effect, significant synergistic effect

Inactive Publication Date: 2013-03-13
JIANGSU SEVENCONTINENT GREEN CHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As for whether the combination of the other three active ingredients has a synergistic effect and what ratio can be used to obtain a satisfactory synergistic effect, it is impossible to predict
In addition, the patent teaches the use of three active ingredients for compound use, which brings a lot of inestimable troubles to practical operations and applications, such as how to combine the ...

Method used

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  • Bactericidal composition containing prothioconazole and trifloxystrobin
  • Bactericidal composition containing prothioconazole and trifloxystrobin
  • Bactericidal composition containing prothioconazole and trifloxystrobin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1 30% Trifloxystrobin Prothioconazole Suspension Concentrate

[0035] The raw material formula of the suspending agent is shown in Table 1, wherein: the number average molecular weight of PEO-PPO-PEO is about 2500, containing PEO30wt%; the thickener is gum arabic; the antifreeze is glycerin; the preservative is sodium benzoate.

[0036] The preparation method of the suspending agent is as follows: add each raw material into the sand mill cylinder according to the formula, and after stirring evenly, pre-disperse it with a high shear machine, then transfer it to a sand mill for sand milling, add sanding medium zirconia beads, and start sanding Grinding, so that the average particle size of the material is below 3 μm, stop sanding after 5 hours, filter, remove the zirconia beads, and obtain.

[0037] The technical indicators of the obtained suspension concentrate are as follows: Suspension rate ≥ 95.0%; pH value 6.0-8.0; sieve analysis (passing through a 75μm sieve...

Embodiment 2

[0038] Example 2 21% Trifloxystrobin Prothioconazole Suspension Concentrate

[0039] The raw material formula of the suspending agent is shown in Table 1, wherein: the number average molecular weight of PEO-PPO-PEO is about 2500, containing PEO30wt%; the thickener is xanthan gum; the antifreeze is propylene glycol; the preservative is butyl p-hydroxybenzoate.

[0040] The preparation method of the suspension is the same as in Example 1, and the technical indicators of the obtained suspension are as follows: suspension rate ≥ 95.0%; pH value 6.0-8.0; sieve analysis (passing through a 75 μm sieve) ≥ 98%; persistent foaming (after 1min) ≤ 25ml; Pourability: residue after pouring ≤ 3.0%, residue after washing ≤ 0.5%; suspension rate ≥ 92% after hot storage at 54±2°C for 30 days; suspension rate ≥92% after cold storage at 0±2°C for 30 days.

Embodiment 3

[0041] Example 3 39% Trifloxystrobin Prothioconazole Suspension Concentrate

[0042] The raw material formula of the suspending agent is shown in Table 1, in which: PEO-PPO-PEO number average molecular weight is about 2000, which contains PEO40wt%; thickener is methyl cellulose and aluminum magnesium silicate (weight ratio 1.25:1); antifreeze It is propylene glycol butyl ether; the preservatives are sodium benzoate and potassium sorbate (weight ratio 1:5).

[0043] The preparation method of the suspension is the same as in Example 1, and the technical indicators of the obtained suspension are as follows: Suspension rate ≥ 94.5%; pH value 6.0-8.0; sieve analysis (through a 75 μm sieve) ≥ 98%; persistent foaming (after 1min) ≤ 25ml; Pourability: residue after pouring ≤3.0%, residue after washing ≤0.5%; suspension rate ≥91% after hot storage at 54±2°C for 30 days; suspension rate ≥91% after cold storage at 0±2°C for 30 days.

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Abstract

The invention relates to a bactericidal composition containing prothioconazole and trifloxystrobin, and the bactericidal composition consists of active components and pesticide preparations as auxiliary components; and especially, the active components consist of prothioconazole and trifloxystrobin in a weight proportion of (0.2-20):1. In the invention, the prothioconazole and the trifloxystrobin are compounded in a special proportion, so that a very significant synergistic interaction effect is obtained. A mass of experiments show that the toxicity to mammals is not increased after the prothioconazole and the trifloxystrobin are compounded. Furthermore, the applicant further discovers that the bactericidal composition containing prothioconazole and trifloxystrobin can be used for further promoting the compounding effect of the prothioconazole and the trifloxystrobin with the adoption of a special wetting dispersant and a dispersion wetting agent, so that both the prothioconazole and the trifloxystrobin play a synergistic role to a maximum extent.

Description

Technical field [0001] The invention belongs to the field of pesticides, and particularly relates to a bactericidal composition containing prothioconazole and trifloxystrobin. Background technique [0002] Prothioconazole, English name: prothioconazole, molecular formula: C 14 H 15 C 12 N 3 OS, chemical name: (RS)-2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-1,2 , 4-triazole-3-thione, is a new broad-spectrum triazole thione fungicide developed by Bayer. The original drug is white crystal and has the advantages of low toxicity, no teratogenicity, no mutagenicity, no toxicity to embryos, and safety to humans, animals and the environment. The mechanism of action of prothioconazole is to inhibit the demethylation of lanosterol, the precursor of sterols in fungi, at the 14- or 24-position of methylenedihydrolanosterol, that is, demethylation inhibitors (DMIs) . Prothioconazole not only has good systemic activity, but also has excellent protect...

Claims

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Application Information

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IPC IPC(8): A01N43/653A01N37/50A01P3/00
Inventor 周炜鞠晓东闫立单顾松山钱海宾乔雪梅
Owner JIANGSU SEVENCONTINENT GREEN CHEM CO LTD
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