Low-temperature resistant lactobacillus with ACE (angiotensin converting enzyme) inhibitory activity

Abstract

A strain of low temperature tolerant lactic acid bacteria with ACE inhibitory activity, which involves a strain of lactic acid bacteria. The low-temperature resistant lactic acid bacterium with ACE inhibitory activity is Lactobacillus plantarum I1, which is preserved in the General Microbiology Center of China Microbiological Culture Collection Management Committee. The preservation address is No. 3, No. 1 Beichen West Road, Chaoyang District, Beijing, and the preservation date is 2012 On September 18, 2009, the deposit number was CGMCCNo.6575. Bacterial strain I1 in the present invention has an ACE inhibition rate of 66%, can tolerate 6% NaCl and 100mg / kg of nitrite and can rapidly produce acid; its growth temperature is 4-40°C, and is suitable for low-temperature fermentation; It has significant protease activity, lipase activity, does not produce mucus, has obvious antibacterial effect on Staphylococcus aureus and Escherichia coli, and can be used as a starter strain for meat products under low temperature conditions.

Description

technical field [0001] The invention relates to a strain of lactic acid bacteria. Background technique [0002] Hypertension is a worldwide problem, affecting 15-20% of adults. Among the various factors that control blood pressure in the human body, renin-angiotensin system (Renia-angiotensin system, RAS) and kallikrein-kinin system (Kallikrein-kinin system, KKS) are two important adjustment system. Among them, angiotensin-converting enzyme (ACE) is an enzyme that plays a key role in the system regulation process and is the main factor that increases blood pressure. Inhibiting the activity of ACE can effectively prevent and treat the occurrence of hypertension. [0003] The research on screening microorganisms with ACE inhibitory activity and making them produce polypeptides with hypotensive function mainly focuses on the research on dairy products. However, the screening of strains with ACE inhibitory activity, low temperature resistance, salt resistance and nitrite res...

AI Technical Summary

Problems solved by technology

[0005] So far, there is no report on the assay of Lactobacillus plantarum ACE inhibitory activity, nor is it used as a relevant report on the development of meat starter strains, and there is no screening out the Report on Lactobacillus plantarum strains with ACE inhibitory activity and can be used as low-temperature fermented meat products

Images