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Traditional Chinese medicine composition used for treating human papillomavirus infection as well as preparation method and application thereof

A technology of human papillomavirus and composition, which is applied in the field of traditional Chinese medicine composition for treating human papillomavirus infection and its preparation, can solve the problems of being unsuitable for infected people and high price, and achieves no toxic side effects and low price. Inexpensive, strict compatibility effect

Active Publication Date: 2013-05-15
南京融昱医药产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Preventive vaccines are still blank in mainland my country, and they are expensive and not suitable for infected people; therapeutic vaccines are still under development internationally

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1: Take bran-fried Atractylodes 8g, bran-fried Atractylodes 12g, Cortex Phellodendron 8g, Coix seed 40g, Chonglou 8g, Banlangen 8g, Hedyotis diffusa 20g, and Smilax smilax 8g, add water to decoct twice, the first time Add water to 8 times the weight of the medicinal material, decoct for 1 hour, add water for the second time to 6 times the weight of the medicinal material, decoct for 1 hour, combine the decoction, 0.07MPa, 60-70 ℃ reduced pressure concentration to 65 ℃ relative density 1.10, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, let stand for 24 hours, the filtrate recovers ethanol under reduced pressure and concentrates, and the filtrate is reduced under 0.07MPa, 65 ℃ The relative density is 1.30 when compressed and concentrated to 65 DEG C, spray drying (the condition is that the inlet air temperature is 120 DEG C, the air outlet temperature is 100 DEG C, the material temperature is 90 DEG C, the atomization pressure is 0.4 MPa...

Embodiment 2

[0023] Example 2: Take bran-fried Atractylodes 12g, bran-fried Atractylodes 8g, Cortex Phellodendron 12g, coix seed 20g, Chonglou 12g, Banlangen 12g, Hedyotis diffusa 40g, and Smilax smilax 12g, add water to decoct twice, the first time Add water to 10 times the weight of the medicinal material, decoct for 1.5 hours, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5 hours, combine the decoction, and concentrate under reduced pressure at 0.07MPa and 60-70 °C to 65 °C The relative density is 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, stand still for 24 hours, the filtrate recovers ethanol under reduced pressure and concentrates, the filtrate is at 0.07MPa, 65 ℃ condition When concentrated under reduced pressure to 65 DEG C, the relative density is 1.25, spray drying (the condition is that the inlet air temperature is 100 DEG C, the outlet air temperature is 80 DEG C, the material temperature is 80 DEG...

Embodiment 3

[0024] Example 3: Take bran-fried Atractylodes 10g, bran-fried Atractylodes 10g, Cortex Phellodendron 10g, coix seed 30g, Chonglou 10g, Banlangen 10g, Hedyotis diffusa 30g, and Smilax smilax 10g together, add water to decoct twice, the first time Add water to 12 times the weight of the medicinal material, decoct for 2 hours, add water for the second time to 10 times the weight of the medicinal material, decoct for 2 hours, combine the decoction, 0.07MPa, 60-70 ℃ reduced pressure concentration to 65 ℃ relative density 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand for 24 hours, the filtrate recovers ethanol under reduced pressure and concentrates, and the filtrate is reduced under 0.07MPa, 65 ℃. Press and condense to 65 DEG C when the relative density is 1.25, spray drying (conditions are that the inlet air temperature is 110 DEG C, the air outlet temperature is 85 DEG C, the material temperature is 85 DEG C, the atomization pressure is ...

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition used for treating human papillomavirus infection. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 8-12 parts of rhizoma atractylodis stir-fried with bran, 8-12 parts of white atractylodes rhizome stir-fried with bran, 8-12 parts of golen cypress, 20-40 parts of coix seed, 8-12 parts of paris polyphylla, 8-12 parts of isatis root, 20-40 parts of oldenlandia diffusa and 8-12 parts of rhizoma smilacis glabrae; and the aim of treating human papillomavirus infection is achieved by tonifying spleen, benefiting qi, promoting diuresis, clearing heat and detoxifying. The invention also provides a preparation method and an application of the traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating human papillomavirus infection, a preparation method and application thereof. Background technique [0002] Human papillomavirus is a kind of papillomavacuolating virus A belonging to Papovaviridae family. It is a spherical DNA virus that can cause squamous epithelial proliferation of human skin and mucous membranes. Symptoms such as common warts and genital warts (condyloma acuminatum). With the rapid increase in the incidence of genital warts among sexually transmitted diseases and the increase of cervical cancer and anal cancer, human papillomavirus (HPV) infection has attracted more and more attention. The infection rate of skin-type HPV is very common, such as common warts, toe warts, and flat warts mentioned above, and the specific infection rate cannot be obtained. The field of gynecology is payi...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/8994A61P31/20
Inventor 任青玲潘林梅邵华
Owner 南京融昱医药产业有限公司
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