Compound, preparation method and application thereof

A technology for separation and purification of compounds, applied in biochemical equipment and methods, methods based on microorganisms, microorganisms, etc., can solve the problem of few studies on metabolites, and achieve the effect of extensive development and application prospects
CN103145683AInactive Publication Date: 2013-06-12SHANGHAI LAIYI BIOMEDICAL RES & DEV CENT
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI LAIYI BIOMEDICAL RES & DEV CENT
Publication Date
2013-06-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a compound with the following structural formula as shown in the specification, and further provides a method of preparing the compound through fermenting and culturing a bacterial strain CGMCC No. 5416 of Phomopsis sp. The compound has good antineoplastic activities for human non-small-cell lung cancer cells, human breast cancer cells, human pancreas cancer cells, human metastasis pancreatic adenocarcinoma cells, human in situ pancreatic adenocarcinoma cells and many other tumor cells, and can be used for preparation of antitumor drugs.
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Description

technical field

[0001] The present invention relates to new compounds, in particular, to a new compound and its preparation method and application. Background technique

[0002] The inventors of the present application obtained a strain of Phomopsis sp. by means of natural screening, named HCCB03519, and the preservation number of this strain is CGMCC No.5416. At present, there are few studies on the metabolites of this strain. Contents of the invention

[0003] The inventors of the present application isolated a compound during the research on the metabolites of Phomopsis sp. strain CGMCC No.5416, which was identified as a new compound by structure.

[0004] Therefore, the primary object of the present invention is to provide a novel compound.

[0005] The second object of the present invention is to provide the preparation method of said compound.

[0006] The third object of the present invention is to provide the application of said compound.

[0007] The fourth ob...

Claims

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