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Novel application of luffa seeds

A technology of loofah seeds and new uses, which is applied in the application field of hypoglycemic health care products and hypoglycemic foods, and can solve the problems that have not yet been reported on hypoglycemic research

Active Publication Date: 2013-07-03
江苏晶红生物医药科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the research on loofah seeds, the current research mainly focuses on the single-chain ribosome inactivating protein isolated from loofah seeds, and there is no research report on its hypoglycemic effect

Method used

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  • Novel application of luffa seeds
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  • Novel application of luffa seeds

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] The luffa seeds of the loofah are taken, shelled, and used for clinical trials, or the loofah seeds are ground into fine powder, mixed with auxiliary materials to make capsules for clinical trials. During the treatment period, the patient took the original hypoglycemic drugs and loofah seeds or loofah seed capsules at the same time, once in the morning and evening, 0.3g each time, twice a day, 7 days a course of treatment. After a course of treatment, measure its fasting blood glucose value. Table 2 is a specific example of 5 type 2 diabetes patients listed.

specific example

[0016]

[0017]

Embodiment 2

[0020] The method described in Example 1 is used to prepare loofah seeds or loofah seed capsules for clinical treatment. During the treatment period, the patient only takes the present invention, once in the morning and evening, 0.3g each time, 2 times a day, a course of treatment in 7 days. After a course of treatment, measure its fasting blood glucose value. Table 2 is a specific example of 5 type 2 diabetes patients listed.

[0021] Table two The present invention treats the concrete example of type 2 diabetes patients

[0022]

[0023] Only enumerate representative examples here, and other clinical experiment results are also consistent with the example results enumerated in Table 2, and are not enumerated here one by one. The results of clinical experiments show that loofah seeds or loofah seed capsules can significantly reduce the fasting blood sugar level of patients and maintain their blood sugar levels stably. And the effect is more significant than that of gene...

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Abstract

The invention belongs to the field of medicine and foods and relates to novel application of luffa seeds. The invention provides novel application of the luffa seeds to preparation of a medicament for treating and preventing diabetes mellitus and complications thereof. A blood sugar regulation medicinal composition or preparation can be prepared from the luffa seeds and one or more vectors or excipients which are acceptable on medicaments. Clinical experiments prove that the luffa seeds or luffa seed capsules can be used in combination with other blood sugar regulation medicaments and the effect of combining the luffa seeds or the luffa seed capsules and other blood sugar regulation medicaments is more obvious than that of separately using the blood sugar regulation medicaments; separate use of the luffa seeds or the luffa seed capsules can also obviously reduce blood sugar of a patient and the medicinal effect of the luffa seeds or the luffa seed capsules is more obvious that that of a common chemical synthetic medicament for preventing diabetes mellitus; administration of the luffa seeds or the luffa seed capsules can also prevent a sugar tolerance patient and a potential diabetic patient (who is fat, has strong genetic background and has irregular living habits) from being converted into a diabetic patient; and the luffa seeds or the luffa seed capsules also has a good treating effect on complications (foot diseases in diabetes) of diabetes mellitus.

Description

technical field [0001] The invention relates to a new application of loofah seeds, in particular to the application in the preparation of hypoglycemic drugs, hypoglycemic health care products and hypoglycemic foods for the treatment or / and prevention of type 2 diabetes and its complications without any side effects. Background technique [0002] Diabetes, known as "diabetes" in ancient times, is caused by the interaction of genetic and environmental factors. Hyperglycemia is the main clinical sign of diabetes. Due to its high incidence and serious complications, diabetes has become a serious disease that endangers human health after tumors and cardiovascular and cerebrovascular diseases. The absolute or relative insufficient secretion of insulin and the decreased sensitivity of target tissue cells to insulin caused by diabetes can cause a series of metabolic disorder syndromes such as protein, fat, water and electrolyte. If not effectively treated, it will eventually lead t...

Claims

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Application Information

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IPC IPC(8): A61K36/42A61P3/10A23L1/29A61K131/00A23L33/00
Inventor 汤建石马永张昊王耀方
Owner 江苏晶红生物医药科技股份有限公司
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