101 results about "Blood sugar regulation" patented technology

The invention discloses a micro-needle patch capable of intelligently regulating blood glucose and a preparation method thereof, and belongs to the field of biomedicine. An intelligent micro-needle part of the micro-needle patch capable of adjusting blood glucose is filled with a medicine for intelligently adjusting blood glucose, and the medicine comprises a carrier material, glucose response sensitive switch factors and medicine molecules. A micro-needle of a micro-needle template is filled with a hydrogel solution containing the medicine through a vacuumizing and centrifugation method; re-centrifugation is carried out, a base of the micro-needle patch is prepared by using the hydrogel solution without the medicine, solidification of the hydrogel material is carried out through a propermethod, and after drying, the micro-needle patch is stripped from the template to obtain the micro-needle patch for intelligently adjusting the blood glucose. The micro-needle patch can puncture skin,insulin is intelligently released in the body according to the blood glucose concentration, and the blood glucose level is intelligently adjusted. According to the micro-needle patch, painless and intelligent response type blood glucose regulation is realized, and diabetes diagnosis and treatment integration is expected to be guided.

The invention provides the use of a whey protein hydrolysate in an edible composition the whey protein hydrolysate being able to induce the cellular release of glucagon-like-peptides and cholecystokinins and / or increasing glucose uptake in target tissues, wherein the whey protein hydrolysate regulates blood glucose levels or results in, or is used for, improving or preventing decline in mental performance and / or for providing a sustained feeling of energy and / or for maintaining or providing a feeling of well-being during the post-prandial period in a subject consuming the composition.

The invention discloses a 3D printing microneedle patch for intelligent blood glucose regulation and a preparation method thereof, belonging to the biomedical field. The 3D printing microneedle patchof the invention is mainly made of photosensitive material with good biocompatibility, and comprises two parts of a substrate and a microneedle array, wherein the microneedle array comprises a plurality of conical microneedles, and the microneedles contain medicaments for intelligently regulating blood sugar, and the medicaments include carrier materials, glucose-responsive sensitive switching factors and medicaments molecules. The 3D printing microneedle patch of the invention is mainly made of photosensitive material with good biocompatibility. Firstly, the three-dimensional model of micro-needle patch is built by using modeling software, and the model is imported into the printing software of 3D printer. Then the 3D printing technology of photocuring is used to solidify the photosensitive material solution containing photoinitiator and drug according to the structure of the three-dimensional model of the micro-needle patch to obtain the 3D printing micro-needle patch. The microneedle patch of the invention can puncture the skin and intelligently release the loaded insulin according to the blood glucose concentration in the body so as to intelligently regulate the blood glucose level. The invention realizes painless, intelligent and responsive blood glucose regulation.

The invention relates to a nutrition composition contributing to regulation of blood sugar and a preparation method thereof. The nutrition composition is prepared from 20-40% of ocean fish oligopeptide, 1-10% of inulin, 1-10% of xylitol, 0.1-5% of lutein esters, 5-30% of oligosaccharide, 10-30% of oat powder, 10-30% of tartary buckwheat flour, 0.1-1% of vitamins, 1-3% of mineral substances and other raw materials. The nutrition composition is suitable for being taken by a hyperglycemia crowd, contains the ocean fish oligopeptide and a plurality of blood sugar regulation factors, can meet the requirement of the human body for nutrition and is good in taste and convenient to eat; compounding of the multiple functional ingredients can achieve synergistic interaction; the nutrition composition has a function of assisting in regulating the blood sugar, can serve as daily meal replacement food for the hyperglycemia crowd, has a certain healthcare effect on the hyperglycemia crowd and has a certain effect of assisting in reducing the blood sugar on diabetics.

The invention belongs to the technical field of medicines and provides a method for adsorbing, purifying and acquiring liquorice residue total flavone with clear component, clear structure, high active substance content and high activity from liquorice residue after extracting glycyrrhizic acid by using macroporous resin as a main material (above 50%), polyamide as an auxiliary material and a compound adsorbing material prepared from one or two MCI mixed at different ratio according to a compound adsorbing purifying method and a medical application thereof at the aspects of blood sugar regulation, liver injury protection, blood lipids regulation, tumor growth suppression, and the like. According to the invention, various adsorbing materials are reasonably combined and designed and the adsorbing purifying technical operation is simple and feasible; the solvent use is safe, environment-friendly and economical; and the liquorice residue total flavone has an obvious restraining effect for two important targets, namely, alpha-glucosidase and PTP1B for preventing and controlling 2-diabetes mellitus, and especially, the restraining effect strength for alpha-glucosidase is at least 10 times higher than that of clinic hypoglycemic drug acarbose.

The invention discloses polygonum cuspidatum tofu. The polygonum cuspidatum tofu adopts polygonum cuspidatum having a health care effect as a raw material and is prepared via procedures including pretreatment of raw materials, slurry regulation, slurry boiling, slurry curdling, curd maintaining, curd breaking, pouring, compressing, cooling and the like; the finished polygonum cuspidatum tofu is good in water retention property and exquisite in taste, has functions of heat elimination, detoxication, wind expelling, dampness removing, cough relieving, phlegm reducing and blood sugar regulation, and is rich in proteins, multiple kinds of microelements and vitamin. According to the invention, a new kind of tofu is provided, meanwhile, the problem that polygonum cuspidatum is only used as a traditional Chinese medicine herb in China for many years, is less in use amount and low in planting benefit, and cannot remarkably increase medicinal herb farmers' income is solved.

The invention discloses meal replacement blood sugar regulation nutrient powder. The meal replacement blood sugar regulation nutrient powder is prepared from the following raw materials in parts by weight: 45 to 50 parts of wheat bran powder, 15 to 20 parts of glucan, 4 to 6 parts of wheat germ, 8 to 10 parts of pumpkin powder, 4 to 6 parts of walnut powder, 4 to 6 parts of almond meal, 1 to 2 parts of soybean meal, 1 to 2 parts of black soya bean powder, 1 to 2 parts of black-eyed pea powder, 1 to 2 parts of red bean powder, 1 to 2 parts of lima bean powder, 1 to 2 parts of mung bean powder, 2 to 3 parts of wolfberry fruit powder, 2 to 3 parts of Chinese yam powder, 2 to 3 parts of pearl barley powder, 3 to 5 parts of Konjac powder, 1 to 2 parts of taurine and 3 to 4 parts of tartary buckwheat powder. The meal replacement blood sugar regulation nutrient powder has the beneficial effects that foods and traditional Chinese medicinal materials are mixed for taking, and the raw materials are blended reasonably, so that absorption of the raw materials by human body is facilitated, a plurality of nutrients are supplemented, blood sugar is regulated reasonably, and the diabetes and complications caused by over high blood sugar can be effectively controlled.

The invention discloses a microneedle patch for intelligently regulating blood sugar and a preparation method thereof, belonging to the field of biomedicine. The intelligent microneedle part of the microneedle patch for regulating blood sugar of the present invention is filled with the medicine for intelligently regulating blood sugar, the medicine carrier material, the sensitive switch factor of glucose response, and the medicine molecule. Fill the drug-containing hydrogel solution into the microneedles of the microneedle template by vacuuming and centrifuging; and prepare the base of the microneedle patch with the drug-free hydrogel solution by centrifuging again, The hydrogel material is solidified by a suitable method, and after drying, the microneedle patch is peeled off from the template to obtain a microneedle patch for intelligently regulating blood sugar. The microneedle patch of the present invention can puncture the skin, and intelligently release the contained insulin in the body according to the blood sugar concentration, so as to intelligently regulate the blood sugar level. Through the invention, painless, intelligent response blood sugar regulation is realized, and it is expected to guide the integration of diagnosis and treatment of diabetes.

The invention relates to the field of active substances, in particular to a needle mushroom extract and a preparation method and application thereof. The needle mushroom extract prepared through the method provided by the invention mainly comprises polysaccharide, protein, vitamins and mineral substances. In vitro experiments show that the needle mushroom extract provided by the invention can inhibit the activity of in vivo alpha-glycosidase. In vivo experiments show that the needle mushroom extract can obviously reduce the blood glucose of II-type diabetic rats, is used for adjusting lipid metabolism disorder, improving insulin resistance, reducing serum free fatty acid level, increasing hepatic glycogen and muscle glycogen storage and repairing damaged pancreas, and has an obvious effect of treating II-type diabetes.

The present invention discloses the use of extracts from the plants of the genus Amaranthus, such as the extracts from Amaranthus mangostanus L. and Amaranthus tricolor L., in lowering the blood glucose level. The present invention further provides anti-diabetes compositions or blood glucose-regulating dietary supplements, which contain the Amaranthus plant extracts as active agent.

The invention relates to a method for preparing a traditional Chinese medicine for reducing blood sugar, adjusting blood fat and resisting DNA injury. 10 to 15 grams of red ginseng and 5 to 7.5 grams of panax notoginseng are taken out and are pulverized to fine powders for standby; 25 to 30 grams of radix astragali, 10 to 15 grams of phellodendron, 10 to 15 grams of coptis root , 15 to 20 grams of salvia miltiorrhiza, 10 to 15 grams of red paeony root, 15 to 20 grams of kudzu root and 10 to 15 grams of shizandra are added with 60-80 mass percent ethanol; the addition amount of the ethanol is 8 to 10 times of the amount of a raw medicinal material; the mixture is subjected to refluxing extraction for 2 to 3 times; each time is kept for 2 to 3 hours; the mixture is filtered; filtrate is combined, ethanol is reclaimed in reduced pressure, and the filtrate after the reclaim of the ethanol is condensed into an extract with the relative density of between 1.10 and 1.15 at the temperature of 40 DEG C; the extract is used for standby; 25 to 35 grams of sealwort, 15 to 20 grams of medlar, 3 to 5 grams of rhubarb and medicine residue after ethanol extraction are added with water the amount of which is 8 to 10 times of the total amount of the sealwort, the medlar, the rhubarb and the medicine residue, and are subjected to refluxing extraction for 2 to 3 times; each time is kept for 2 hours; the extract is filtered; filtrate is combined and condensed into an extract with the relative density of between 1.10 and 1.15 at the temperature of 40 DEG C; the ethanol extracted extract are combined, sprayed and dried; the temperature of an inlet is between 140 and 160 DEG C; and the extract is added with 10 to 15 grams of fine powders of the red ginseng, 5 to 7.5 grams of fine powders of the panax notoginseng and proper amount of calcium carbonate to prepare a granular formulation. The Chinese medicine preparation can obviously reduce blood sugar, adjust blood fat, resist DNA injury.

The invention relates to a tea bag beverage, in particular to ganoderma lucidum tea bag. The tea bag is prepared by the following raw materials in percentage by weight: 1 to 20 percent of ganoderma lucidum, 1 to 25 percent of American ginseng, 0.5 to 30 percent of pearl, 1 to 25 percent of eucommia, 1 to 25 percent of medlar, 1 to 30 percent of prepared rhizome of manyflower solomonseal, 1 to 30 percent of hawkthorn, 1 to 30 percent of red sage root, 1 to 30 percent of fructus momordicae, 1 to 30 percent of seed of spine date and 1 to 30 percent of chitosan. The tea bag is prepared by using the ganoderma lucidum as a main raw material and adding the American ginseng, pearl, eucommia, medlar, prepared rhizome of manyflower solomonseal, hawkthorn, red sage root, fructus momordicae, seed of spine date and chitosan, so that the tea bag has a higher medical value and has the health-care effects of regulating blood fat and blood sugar, regulating blood pressure, improving sleeping quality, loosening the bowel to relieve constipation and the like; and the tea bag integrates the functions of health care and beverage and is quite suitable for people to take daily.