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Chewing gum for preventing and treating oral ulcer after chemotherapy

A technology for oral ulcers and chewing gum, which is applied in the field of chewing gum, can solve the problems of poor curative effect of health care chewing gum, and achieve the effects of improving bioavailability, reducing irritation, and increasing safety

Inactive Publication Date: 2013-07-17
THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Aiming at the problem that the curative effect of health-care chewing gum for preventing and treating oral ulcers after chemotherapy is relatively poor, the present invention provides a chewing gum for preventing and treating oral ulcers after chemotherapy, which can effectively prevent and treat oral ulcers caused by different causes after chemotherapy; it can also reduce the effect of drugs on the gastrointestinal tract. Road stimulation, reduce the occurrence of adverse reactions, increase safety; good taste, easy to take

Method used

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  • Chewing gum for preventing and treating oral ulcer after chemotherapy
  • Chewing gum for preventing and treating oral ulcer after chemotherapy
  • Chewing gum for preventing and treating oral ulcer after chemotherapy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1: The preparation method of the chewing gum for preventing and treating post-chemotherapy oral ulcers comprises the following specific steps:

[0043] The first step is to weigh the chewing gum ingredients in proportion; weigh 25 grams of edible gum base, 20 grams of maltose syrup, 35 grams of xylitol, and 20 grams of sorbitol;

[0044] The second step is to mix xylitol and sorbitol; mix the weighed xylitol and sorbitol evenly, put them into an oven at 80°C for sterilization, and obtain a mixture of xylitol and sorbitol;

[0045]The third step is to soften the edible gum base; heat the weighed edible gum base (heat the edible gum base to 80-120°C and stir thoroughly, stop heating after 5-10 minutes) to soften; at the same time, heat the weighed maltose syrup to 100°C;

[0046] The fourth step is to prepare the chewing gum ingredients; uniformly mix the mixture of xylitol and sorbitol obtained in the second step, the softened edible gum base obtained in the ...

Embodiment 2

[0051] Embodiment 2: The preparation method of the chewing gum for preventing and treating post-chemotherapy oral ulcers comprises the following specific steps:

[0052] The first step is to weigh the chewing gum ingredients in proportion; weigh 30 grams of edible gum base, 25 grams of maltose syrup, 35 grams of xylitol, and 10 grams of sorbitol;

[0053] The second step is to mix xylitol and sorbitol; mix the weighed xylitol and sorbitol evenly, put them into an oven at 80°C for sterilization, and obtain a mixture of xylitol and sorbitol;

[0054] The third step is to soften the edible gum base; heat the weighed edible gum base (heat the edible gum base to 80-120°C and stir thoroughly, stop heating after 5-10 minutes) to soften; at the same time, heat the weighed maltose syrup to 100°C;

[0055] The fourth step is to prepare the chewing gum ingredients; uniformly mix the mixture of xylitol and sorbitol obtained in the second step, the softened edible gum base obtained in th...

Embodiment 3

[0060] Embodiment 3: The preparation method of the chewing gum for preventing and treating oral ulcer after chemotherapy comprises the following specific steps:

[0061] The first step is to weigh the chewing gum ingredients in proportion; weigh 26 grams of edible gum base, 21 grams of maltose syrup, 40 grams of xylitol, and 13 grams of sorbitol;

[0062] The second step is to mix xylitol and sorbitol; mix the weighed xylitol and sorbitol evenly, put them into an oven at 80°C for sterilization, and obtain a mixture of xylitol and sorbitol;

[0063] The third step is to soften the edible gum base; heat the weighed edible gum base (heat the edible gum base to 80-120°C and stir thoroughly, stop heating after 5-10 minutes) to soften; at the same time, heat the weighed maltose syrup to 100°C;

[0064] The fourth step is to prepare the chewing gum ingredients; uniformly mix the mixture of xylitol and sorbitol obtained in the second step, the softened edible gum base obtained in the...

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Abstract

The invention relates to a chewing gum for preventing and treating oral ulcer after chemotherapy. The chewing gum is composed of chewing gum ingredients and drugs used for preventing and treating oral ulcer. Each 100 g of the chewing gum for preventing and treating oral ulcer after chemotherapy comprises the following drugs used for preventing and treating oral ulcer: 5 to 10 mg of a recombinant human granulocyte colony stimulating factor, 5 to 10 mg of folic acid, 5 to 10 mg of metronidazole, 20 to 50 mg of lidocaine, 5 to 20 mg of cimetidine and 2.5 to 10 mg of vitamin B2, with the balance being the chewing gum ingredients. The chewing gum ingredients comprise, by weight, 25 to 30% of an edible gum base, 20 to 25% of maltose syrup, 35 to 45% of xylitol and 10 to 20% of sorbitol. The chewing gum provided by the invention can effectively prevent and treat oral ulcer resulting from different causes after chemotherapy, mitigate stimulation of the drugs on gastrointestinal tracts, reduce occurrence of adverse reactions and improve safety, has good taste and is convenient to take.

Description

technical field [0001] The invention relates to a chewing gum, in particular to a chewing gum for preventing and treating oral ulcers after chemotherapy. Background technique [0002] As a well-known snack between meals, chewing gum is suitable for all ages. It can not only freshen the breath, produce body fluid and condense fragrance, and refresh the throat, but also has the effects of relieving stress, enhancing memory, and preventing tooth decay. Domestic studies have found that the occurrence of oral ulcers after teeth cleaning with chewing gum reduces infection complications, and patients can eat and sleep normally, which is conducive to the smooth progress of chemotherapy. The chewing gum is delicious and cheap, easy for patients to chew, easy to accept, and has no adverse reactions. [0003] With the continuous research and development of new chemotherapeutic drugs, the application of chemotherapeutic drugs to treat malignant tumors has become a routine treatment met...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/19A61K9/68A61P1/02A61K31/4164A61K31/167A61K31/525
Inventor 符刚余谨张佳思
Owner THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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