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Chinese and western medicine compound preparation containing tilmicosin and preparation method thereof

A technology of tilmicosin and compound preparations, which is applied in the field of Chinese and Western medicine compound preparations and its preparation, can solve the problems of cumbersome extraction of Chinese medicine components, troublesome transportation of solution preparations, and high market purchase prices, so as to save production processes and reduce drug consumption. Residual, immune-boosting effect

Inactive Publication Date: 2013-09-04
GUANGDONG WENS DAHUANONG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when tilmicosin is used alone, the course of treatment is longer, the dosage is larger, and the cost is high, which is not conducive to popularization and application in actual production.
[0005] The Chinese invention patent with the patent number ZL 201110066379.2 discloses a tilmicosin compound preparation and its preparation method and application. The tilmicosin compound preparation uses Among the veterinary drugs, the synthetic drug pidotimod has not been approved for use in animals or food animals, because there is no relevant research on the safety of pidotimod in animal applications and drug residues in food animals , which limits the practical application of the compound preparation in veterinary drug production and veterinary clinic
[0006] The Chinese invention patent with the patent number ZL 201010503385.5 discloses a compound tilmicosin oral liquid and its preparation method. The compound tilmicosin preparation uses Traditional Chinese medicine astragalus extract - astragalus polysaccharide, traditional Chinese medicine isatidis extract - isatidis polysaccharide, monomer component extracted from honeysuckle - chlorogenic acid, these extracted traditional Chinese medicine ingredients are cumbersome to extract by themselves, and the market purchase price is high, especially chlorogenic acid , the quality is difficult to control
Moreover, the compound tilmicosin preparation needs to add various co-solvents and preservatives, which is easy to cause environmental pollution, and its preparation method is troublesome. The various co-solvents and preservatives that need to be added need to be heated for production, and the prepared solution preparations are transported trouble also adds to shipping costs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A Chinese and Western medicine compound preparation containing tilmicosin, which is composed of the following components by weight percentage: 20% tilmicosin, 6% taurine, 20% astragalus, 20% Folium Isatidis, and 20% Radix Radix , Starch 14%.

[0033] The preparation method of the above-mentioned Chinese and Western medicine compound preparation containing tilmicosin is as follows:

[0034] 1) Premixing taurine and starch to obtain a premixed material;

[0035] 2) The premixed material obtained in step 1) is mixed with tilmicosin, astragalus superfine powder, Folium Isatidis superfine powder, isatis root superfine powder and the remaining starch to obtain the product.

Embodiment 2

[0037] This embodiment is further improved on the basis of Example 1. The difference is that: the astragalus, Radix Radix, and Folium Folium are all pulverized to ultrafine powder, and the average particle diameters of the Radix Astragali, Radix Radix, and Folium Folium are all between More than 300 mesh.

[0038] Preparation:

[0039] 1) Pulverize astragalus, isatidis, and Folium baicalensis with ultra-fine pulverization equipment, so that their average particle size reaches more than 300 mesh;

[0040] 2) Premixing taurine and starch to obtain a premixed material;

[0041] 3) The premixed material obtained in step 2) is mixed with tilmicosin, astragalus superfine powder, Folium Isatidis superfine powder, isatis root superfine powder and the remaining starch to obtain the product.

Embodiment 3

[0043] A Chinese and Western medicine compound preparation containing tilmicosin, which consists of the following components by weight percentage:

[0044] Tilmicosin 20%, Taurine 5%, Astragalus 30%, Radix Radix 30%, Folium Folium 10%, Starch 5%.

[0045] The preparation method of the above-mentioned Chinese and Western medicine compound preparation containing tilmicosin is as follows:

[0046] 1) Pulverize astragalus, isatidis, and Folium baicalensis with ultra-fine pulverization equipment, so that their average particle size reaches more than 300 mesh;

[0047] 2) Premixing taurine and starch to obtain a premixed material;

[0048] 3) The premixed material obtained in step 2) is mixed with tilmicosin, astragalus superfine powder, Folium Isatidis superfine powder, isatis root superfine powder and the remaining starch to obtain the product.

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PUM

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Abstract

The invention discloses a Chinese and western medicine compound preparation containing tilmicosin. The Chinese and western medicine compound preparation containing tilmicosin comprises the following components by mass percent: 2-30% of tilmicosin, 0.5-10% of taurine, 5-30% of milkvetch, 5-30% of isatis root, 5-30% of indigowoad leaf and the balance of officinal filling auxiliary material. The invention also discloses a preparation method of the Chinese and western medicine compound preparation containing tilmicosion. The Chinese and western medicine compound preparation containing tilmicosion has the advantages of stable effect, convenience in application and easiness in preparation when being used for treating respiratory diseases of beasts and birds.

Description

[0001] Technical field [0002] The invention involves the field of veterinary medicine technology, and specifically involves a compound preparation method and its preparation methods containing the Chinese and Western medicines containing rice. [0003] Background technique [0004] Tyomi Kaoxing is a semi -synthesis of large -ringed laidone and poultry antibiotics developed successfully by the British ELANCO Animal Health Products Company in the 1980s.The spiral body and other inhibitory effects have significant effects on the infectious diseases caused by sensitive bacteria such as pigs, cattle, sheep and other animals, especially livestock and poultry respiratory tract infections.As a new type of livestock and poultry special antibiotics, its research has continued to deepen.The latest research shows that it can inhibit bacterial protein synthesis and promote the body's defense function (synergistic macrophages produce sterilization effects, promote neutral granulocyte apopto...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/855A61K36/704A61K36/481A61P11/00A61P31/04A61P31/12A61K31/185A61K31/706
CPCY02A40/70
Inventor 刘小艳方烦虎陈瑞爱袁照红湛穗璋
Owner GUANGDONG WENS DAHUANONG BIOTECH