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Medicinal composition for treating type-II diabetes

A composition and diabetes technology, applied in the field of preparation of type II diabetes mellitus with a composition containing propranolol and traditional Chinese medicine extracts, can solve the problems of slow onset and other problems, and achieve the elimination of slow onset, convenient use, and stable effect

Inactive Publication Date: 2018-03-23
SUZHOU SCI&TECH TOWN HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are also some shortcomings in traditional Chinese medicine, such as slow onset of action, need to be used under the guidance of experienced Chinese medicine practitioners, etc.

Method used

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  • Medicinal composition for treating type-II diabetes
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  • Medicinal composition for treating type-II diabetes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A pharmaceutical composition for treating type II diabetes, wherein the pharmaceutical composition is composed of propranolol and a Chinese medicine extract in a weight ratio of 1:120, wherein the Chinese medicine extract is prepared from the following raw materials in parts by weight into:

[0021] 25 parts of aconite, 20 parts of cardamom, 18 parts of Pulsatilla, 25 parts of honeysuckle, 15 parts of Trichosanthes, 12 parts of Polygonum cuspidatum, 8 parts of mitten grass, 12 parts of Shenjin grass, 10 parts of purslane, 7 parts of star anise lotus 6 parts, 6 parts of Geranium purple back, 3 parts of powder bud lettuce.

[0022] The preparation method of this Chinese medicine extract is:

[0023] Soak the above-mentioned medicinal materials in water with 6 times the dose by weight for 1 hour, boil the water for 2 hours, filter, concentrate to a thick paste, and dry.

[0024]

[0025] Wherein the pharmaceutical composition is composed of propranolol and traditional...

Embodiment 2

[0027] A pharmaceutical composition for treating type II diabetes, wherein the pharmaceutical composition is composed of propranolol and a Chinese medicine extract in a weight ratio of 1:120, wherein the Chinese medicine extract is prepared from the following raw materials in parts by weight into:

[0028] 45 parts of aconite, 36 parts of cardamom, 30 parts of Pulsatilla chinensis, 32 parts of honeysuckle, 20 parts of Trichosanthes, 18 parts of Polygonum cuspidatum, 16 parts of Deer's Grass, 18 parts of Shenjin grass, 20 parts of purslane, 12 parts of star anise lotus 10 parts, 10 parts of Geranium purple back, 5 parts of powder bud lettuce.

[0029] The preparation method of this Chinese medicine extract is:

[0030] Soak the above-mentioned medicinal materials in water with 6 times the dose by weight for 1 hour, boil the water for 2 hours, filter, concentrate to a thick paste, and dry.

[0031]

[0032] Wherein the pharmaceutical composition is composed of propranolol a...

Embodiment 3

[0033] Embodiment 3 pharmacological action research

[0034] With reference to Zhang Juntian editor-in-chief, "Modern Pharmacological Test Methods" (volume 1), Peking Union Medical College Press, pages 984-985, the method disclosed in "Second Section 2 Animal Model Similar to Type 2 Diabetes" to establish an experimental Obese and diabetic rat models were used to conduct pharmacodynamic tests of the medicinal composition of the present invention for lowering blood sugar.

[0035] Test group:

[0036] 1. Model control group: After the animal model is successfully established, normal saline is administered into the stomach;

[0037] 2. Pure Chinese medicine group: 2 g / kg body weight of the extract as mentioned above was administered into the stomach;

[0038] 3. Propranolol group: 15mg / kg body weight orally;

[0039] 4. Composition group: 15 mg / kg body weight of propranolol + 2 g / kg body weight of the extract described in Example 1 orally.

[0040]

[0041] This table sho...

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PUM

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Abstract

The invention relates to a medicinal composition for treating type-II diabetes, which is characterized by being composed of propranolol and a traditional Chinese medicine extract according to weight ratio of 1:120. The traditional Chinese medicine extract is prepared from, by weight, 25-45 parts of radix aconiti carmichaeli, 20-36 parts of alpinia katsumadai, 18-30 parts of pulsatilla chinensis, 25-32 parts of honeysuckle stems, 15-20 parts of trichosanthes kirilowii, 12-18 parts of polygonum cuspidatum, 8-16 parts of pyrola, 12-18 parts of lycopodium clavatum, 10-20 parts of purslane, 7-12 parts of dysosma auranticocaulis, 6-10 parts of begonia fimbristipula and 3-5 parts of chondrilla juncea. The medicinal composition employs the traditional Chinese medicines which have effects of strengthening body resistance and eliminating evil, reinforcing body and supporting vitality, and treating the disease from sources. Being combined with the propranolol, the problem of slow effect of the traditional Chinese medicines is eliminated. By combining Chinese and Western medicines, the medicinal composition has quick treatment effect, can strengthen body and improving body resistance, and hasstable effects and convenience in usage when being used for treating the type-II diabetes.

Description

technical field [0001] The invention relates to a Chinese and Western medicine composition for treating diabetes, specifically a composition containing propranolol and a Chinese medicine extract, and the use of the composition in preparing medicine for treating type II diabetes. Background technique [0002] Diabetes is a common metabolic disease, and its incidence is related to factors such as genetic factors, lifestyle, diet structure and age. According to the pathological characteristics of patients, diabetes can be divided into two types: type Ⅰ diabetes and type Ⅱ diabetes. Type Ⅱ diabetes is also called non-insulin-dependent diabetes, of which the latter accounts for more than 90%. The main characteristics of type Ⅱ diabetes are: decreased insulin secretion and insulin action of pancreatic β cells, that is, insulin resistance. [0003] In addition to insulin, most of the drugs for clinical treatment of type II are chemical drugs. The widely used drugs can be roughly d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P3/10A61K31/138
CPCA61K31/138A61K36/12A61K36/185A61K36/28A61K36/29A61K36/355A61K36/428A61K36/704A61K36/71A61K36/714A61K36/9062A61K2300/00
Inventor 李惠芬
Owner SUZHOU SCI&TECH TOWN HOSPITAL