Method and device for producing ions used for analysis under low pressure

An ion and ion focusing technology, applied in the parts of the particle separator tube, particle separation tube, ion source/gun, etc., can solve the problems of loss and insufficient sensitivity of the ion source, achieve high sensitivity, increase the application range, improve the The effect of sensitivity
CN103295873AActive Publication Date: 2013-09-11SHIMADZU SEISAKUSHO CO LTD
13 Cites 42 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHIMADZU SEISAKUSHO CO LTD
Publication Date
2013-09-11

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention relates to a method and device for producing ions used for analysis, in particular to an ionization method and device for producing ions through multiple modes under the lower pressure and enabling multiple ion sources to be compounded and used. According to the method and device, an electrospray ion source and other desorbing / ionization devices (such as laser desorbing ion sources) are placed in the same vacuum cavity and act on sample molecules in the vacuum cavity independently or commonly, and the irons produced by ionization are fed into an ion analyzer to be analyzed through an ion focusing device.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a method and device for generating ions for analysis, especially an ionization method and device for generating ions in multiple ways under relatively low pressure and using the multiple ion sources in combination. Background technique

[0002] For mass spectrometry analysis of macromolecules (such as proteins, peptides, and DNA molecules), softer ionization methods are usually required. The ionization methods currently used in this field generally include: electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI). These two ionization methods have their own advantages and disadvantages. For example, ESI can generate multi-charged ions, and with high-resolution mass spectrometry, it can conveniently characterize macromolecules. Therefore, ESI sources have been widely used at present, but ESI generally cannot meet the requirements of high ionization at the same time. Throughput and high sensitivity; ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More