Unlock instant, AI-driven research and patent intelligence for your innovation.

Natural medicine extractive and preparation method and uses thereof

A technology of natural medicine and extract, which is applied in the direction of drug combination, pharmaceutical formula, antineoplastic drugs, etc.

Inactive Publication Date: 2013-10-16
石强
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Natural medicine extractive and preparation method and uses thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of the concentrated extract of Phellodendron tangerine peel decocted in water

[0033] According to the compatibility ratio of 1:1, take Cortex Phellodendron and orange peel, soak in distilled water, heat and decoct, filter, add distilled water to the dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and filter with ultrafiltration membrane. Drying under reduced pressure, that is.

[0034] (2) Preparation of Phellodendron Phellodendri Ethyl Acetate Extract

[0035] Phellodendron cortex is crushed, soaked in 95% alcohol for 3 times, combined with ethanol extract, brown extract obtained by distillation under reduced pressure, dispersed in water, extracted with water, diethyl ether and ethyl acetate in sequence, part of ethyl acetate is distilled under reduced pressure, and dried to obtain phellodendron acetic acid ethyl ester extract.

[0036] (3) Prepar...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a natural medicine extractive and a preparation method and purposes thereof. The natural medicine extractive is prepared from phellodendron amurense pericarpium citri reticulatae water decocted condensed extractives, phellodendron amurense ethyl acetate extractives and nobiletin according to the ratio of (2-8):(1-5):(5-7). The composition has a great curative effect on cancer chemotherapy related diarrhea, and meanwhile has a synergistic effect on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine extract, more specifically relate to a kind of natural medicine extract that is made up of Phellodendron tangerine peel decoction concentrated extract, Phellodendron tangerine peel extract and nobiletin, the preparation method of this natural medicine extract And the use of the natural medicine extract in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61P1/12A61P35/00A61K31/352
Inventor 石强
Owner 石强
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com