Skin disinfection gel and its application

A skin disinfection and gel technology, applied in the field of disinfectants, can solve the problems of difficulty in adapting to long-term surgery, poor long-term killing effect, and weak activity of filamentous fungi, so as to avoid secondary cross-infection and inhibit the reproduction of pathogens , to avoid the effects of drug resistance

Active Publication Date: 2013-10-23
RIZHAO ZHONGSHENG MARINE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Triclosan has some activity against mycobacteria and candida, but less activity against filamentous fungi
It can be used to clean and disinfect the skin of hands, but the disinfection gel has poor long-term killing effect during use
Chinese patent application CN1498538A discloses a marine biological disinfectant with chitin, alginic acid, agarose gelatin, Yujie pure DP300, and cedarwood alcohol as active ingredients. The defect of poor long-term antivirus effect makes it difficult to adapt to the needs of long-term surgery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: Gel for skin disinfection of the present invention

[0036] A gel used for skin disinfection, the active ingredients include chitosan, chitosan oligosaccharide, chlorhexidine, baicalin, sodium alginate, agarose, and peppermint extract. Among them, the concentration of chitosan is 3%, the concentration of chitooligosaccharide is 4%, the concentration of chlorhexidine is 1.2%, the concentration of baicalin is 3.7%, the concentration of sodium alginate is 1%, the concentration of agarose is 2.5%, and mint extract 3%.

[0037] Taking the preparation of 1000 g of gel as an example, each kg of gel contains 30 g of chitosan, 40 g of chitosan oligosaccharide, 12 g of chlorhexidine, 37 g of baicalin, 10 g of sodium alginate, 25 g of agarose, and 30 g of peppermint extract. The specific preparation method is to add 30g of chitosan, 25g of agarose and 40g of chitosan oligosaccharide into 816 ml of purified water, and fully dissolve it with a high-speed disperser...

Embodiment 2-6

[0038] Embodiment 2-6 gel agent for skin disinfection of the present invention

[0039] The skin disinfectant prescription is as shown in Table 1, and the preparation method is the same as the preparation method of the skin disinfectant gel in Example 1.

Embodiment 2- Embodiment 6

[0040] The percentage composition of table 1 embodiment 2-embodiment 6 skin antiseptic gel

[0041]

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PUM

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Abstract

Belonging to the technical field of disinfection, the invention discloses a skin disinfection gel to solve the disadvantages of existing disinfection technologies, especially preoperative disinfection technologies. The skin disinfection gel is composed of the following active components by mass: 1.5%-6% of chitosan, 1.5-10% of chitosan oligosaccharide, 2%-8% of baicalin, 0.5%-2% of chlorhexidine, 0.5%-1.5% of sodium alginate, 2%-5% of agarose, and 1.5%-5% of a mint extract. And the disinfection effect is good. The disinfection gel disclosed in the invention can be used for hand disinfection or skin disinfection in sanitary disinfection or preoperative disinfection, and with excellent disinfection effects and lasting function, it has very good application prospects and economic benefits.

Description

technical field [0001] The invention belongs to the technical field of disinfectants, and in particular relates to a skin disinfectant gel and its application. Background technique [0002] Bacteria on the skin can be divided into transient and resident bacteria. Resident bacteria reside beneath the epithelial cells of the stratum corneum of the skin and can also be found on the skin surface. Resident bacteria have two main protective functions: anti-foreign microorganisms and competition for nutrients in the micro-ecosystem, and are usually rarely related to infection. Transient bacteria, generally attached to the epidermis of the skin, can survive and partially reproduce on the skin surface. Transient bacteria are often obtained through direct contact between medical staff and patients or contaminated by contact with environmental surfaces near patients, which is closely related to nosocomial infection. Therefore, various clinical treatments and diagnoses require skin d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61K9/06A61P31/02A61K31/352A61K31/155A61K31/722A61K31/702
Inventor 焦念强刘中伟杜广青
Owner RIZHAO ZHONGSHENG MARINE BIOTECH
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