Surface plasmon resonance system and its detection method
A technology of surface plasmon and detection light, which is applied in the field of ion resonance system and its detection, and can solve the problems of small measurement range and so on.
Active Publication Date: 2016-03-02
山东深大光学科技有限公司
View PDF3 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
[0004] The purpose of the embodiment of the present invention is to provide a surface plasmon resonance system, aiming to solve the problem of the small measurement range of the existing surface plasmon resonance system
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment Construction
[0029] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.
[0030] In the embodiment of the present invention, broadband light is generated first, narrowband light is obtained from the broadband light, and polarized light is obtained from the narrowband light to make it into modulated polarized light, and then the modulated polarized light is divided into probe light and reference light, so that The detection light is projected onto the sensing surface of the prism, and the detection light intensity distribution reflected by the sensing surface is recorded to form a detection image. During one modulation cycle of the detection light, the imaging mechanism a...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention is suitable for the technical field of photoelectric detection, and provides a surface plasma resonance system and a detection method thereof. The surface plasma resonance system is composed of a detection light path and a reference light path. According to the invention, the detection light path is used for acquiring plurality sets of first detection images and second detection images under different narrowband optical wavelengths. Through searching for optimal narrowband optical wavelengths for various detection points of a sensing surface to produce SPR phenomenon from the plurality sets of first detection images and second detection images, a detection sample reflective index change is calculated, such that phase SPR high-sensitivity detection is completed. Both the plurality sets of first detection images and second detection images comprise SPR phase and spectral wavelength information. Through spectral scanning which is changing the narrowband optical wavelengths, a maximal dynamic range is obtained. Therefore, an application requirement of the surface plasma resonance system for large dynamic range is satisfied, and high sensitivity is ensured. Also, the surface plasma resonance system realizes plane detection which has extremely higher efficiency than that of point detection.
Description
technical field [0001] The invention belongs to the technical field of photoelectric detection, and in particular relates to a surface plasmon resonance system and a detection method thereof. Background technique [0002] Surface Plasmon Resonance (SPR) is an emerging sensing technology, which has the advantages of high sensitivity, high throughput, easy to achieve specific detection and real-time performance, and does not require labeling. It has been widely used in biology and medicine. , food quality and safety, chemical and environmental monitoring and other industries, especially online real-time detection between DNA and protein, between protein molecules, and between biomolecules such as drug-protein, nucleic acid-nucleic acid, antigen-antibody, receptor-ligand, etc. interaction etc. [0003] At present, SPR technologies mainly include angle-type SPR, spectral-type SPR and phase-type SPR. Among them, the phase-type SPR sensing technology has higher sensitivity, but t...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/552
Inventor 邵永红顾大勇屈军乐牛憨笨
Owner 山东深大光学科技有限公司