Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof
A technology of effective parts and compositions, applied in the field of traditional Chinese medicine compositions, can solve the problems of indefinite curative effect, lack of radical cure methods, and easy recurrence, etc., and achieve the effect of no toxic side effects, simple and easy preparation method, and high yield
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Embodiment 1
[0018] Take 30g of Luo Han Guo, 8g of narcissus, 25g of lychee grass, 6g of amethyst and 31g of fenugreek, grind them into coarse powder, add 12 times the amount of water, decoct 3 times, and decoct for 1 hour each time; filter the decoction and combine the filtrate, reduce Concentrate under pressure to a paste with a relative concentration of 1.14, add ethanol to make the alcohol content 69%, let it stand overnight, recover ethanol, and obtain 1000ml of concentrated solution, take simple syrup, add the above concentrated solution, and adjust the pH to 4. Add distilled water to 5000ml, stir evenly, divide into 15ml glass bottles after fine filtration, and pack to obtain oral liquid.
[0019] This product is a yellow-brown clear liquid, which will not become turbid within half a year, with a pH of about 4 and a total solid of about 9%.
Embodiment 2
[0021] 100 patients were clinically observed, all of whom had obvious clinical symptoms of rosacea and were diagnosed by clinicians.
[0022] Oral the oral liquid that embodiment 1 makes, every day 2 times, each 15ml. Medication time is 10 days.
[0023] After 10 days, the statistical results of patients using the oral liquid obtained in Example 1 are shown in Table 1.
[0024] Efficacy criteria: Marked effect includes recovery and improvement. Recovery refers to the complete disappearance of rashes (such as erythema, papules, pustules, etc.), subjective symptoms disappear, skin color returns to normal, and no new rash appears; improvement refers to the disappearance of more than 70% of the rash , new rashes appear less, and flushing subsides. The skin still has mild erythema, or a few small papules. Ineffective means that the symptoms do not improve, or even intensify, the flushing remains the same, and new rashes still appear, sometimes with exudation, pain and swelling. ...
Embodiment 3
[0029] The oral liquid prepared in Example 1 was used to administer ICR mice with a body weight of 20-25 g, half male and half male, and the administration was continued for 90 days.
[0030] After pre-testing, the toxicity of the lotion prepared in Example 1 was very low, and the LD50 could not be measured, so the maximum daily dosage was determined for mice. The maximum dosage is 150ml / d. After 90 days, there is no case of poisoning death, and all of them are alive and healthy. This proves that the oral liquid made from the composition of the present invention will not cause toxic and side effects to the human body.
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