Traditional Chinese medicine effective part composition for treating rosacea and preparation method thereof

A technology of effective parts and compositions, applied in the field of traditional Chinese medicine compositions, can solve the problems of indefinite curative effect, lack of radical cure methods, and easy recurrence, etc., and achieve the effect of no toxic side effects, simple and easy preparation method, and high yield

Inactive Publication Date: 2013-12-11
广州市云桥生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern Western medicine still lacks a radical cure. Generally, antibacterial, anti-inflammatory, sedative, and B vitamin supplementation are used for treatment. The curative effect is uncertain and it is easy to relapse.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Take 30g of Luo Han Guo, 8g of narcissus, 25g of lychee grass, 6g of amethyst and 31g of fenugreek, grind them into coarse powder, add 12 times the amount of water, decoct 3 times, and decoct for 1 hour each time; filter the decoction and combine the filtrate, reduce Concentrate under pressure to a paste with a relative concentration of 1.14, add ethanol to make the alcohol content 69%, let it stand overnight, recover ethanol, and obtain 1000ml of concentrated solution, take simple syrup, add the above concentrated solution, and adjust the pH to 4. Add distilled water to 5000ml, stir evenly, divide into 15ml glass bottles after fine filtration, and pack to obtain oral liquid.

[0019] This product is a yellow-brown clear liquid, which will not become turbid within half a year, with a pH of about 4 and a total solid of about 9%.

Embodiment 2

[0021] 100 patients were clinically observed, all of whom had obvious clinical symptoms of rosacea and were diagnosed by clinicians.

[0022] Oral the oral liquid that embodiment 1 makes, every day 2 times, each 15ml. Medication time is 10 days.

[0023] After 10 days, the statistical results of patients using the oral liquid obtained in Example 1 are shown in Table 1.

[0024] Efficacy criteria: Marked effect includes recovery and improvement. Recovery refers to the complete disappearance of rashes (such as erythema, papules, pustules, etc.), subjective symptoms disappear, skin color returns to normal, and no new rash appears; improvement refers to the disappearance of more than 70% of the rash , new rashes appear less, and flushing subsides. The skin still has mild erythema, or a few small papules. Ineffective means that the symptoms do not improve, or even intensify, the flushing remains the same, and new rashes still appear, sometimes with exudation, pain and swelling. ...

Embodiment 3

[0029] The oral liquid prepared in Example 1 was used to administer ICR mice with a body weight of 20-25 g, half male and half male, and the administration was continued for 90 days.

[0030] After pre-testing, the toxicity of the lotion prepared in Example 1 was very low, and the LD50 could not be measured, so the maximum daily dosage was determined for mice. The maximum dosage is 150ml / d. After 90 days, there is no case of poisoning death, and all of them are alive and healthy. This proves that the oral liquid made from the composition of the present invention will not cause toxic and side effects to the human body.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine effective part composition for treating rosacea and a preparation method thereof. The traditional Chinese medicine effective part composition is prepared by the following raw materials in parts by weight: siraitia grosvenorii, narcissus, salvia plebeian and fenugreek. The traditional Chinese medicine effective part composition provided by the invention can be prepared into medicine for treating rosacea, and has effects of clearing lung stomach and purging heat, clearing heat and removing toxicity, and activating blood and dissolving stasis, can be used for treating rosacea obviously, and has the advantages of no toxicity or side effects, and high security.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition of effective parts of traditional Chinese medicines for treating rosacea and a preparation method thereof. Background technique [0002] Rosacea is a common chronic skin disease, more common in middle-aged people with seborrhea. Although the disease generally has no serious harm to human health, and the subjective symptoms are also relatively mild, it often brings pain and troubles to the patient psychologically because it hinders the beauty of the face. Modern western medicine still lacks a radical cure method, and generally adopts methods such as antibacterial and anti-inflammatory, sedation, supplementing B vitamins, etc., the curative effect is not exact, and it is easy to relapse. Contents of the invention [0003] The object of the present invention is to provide a Chinese medicine effective part composition for treating rosacea, whi...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P17/00A61K33/14
Inventor 张群
Owner 广州市云桥生物科技有限公司
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