Preparation and Application of Molecularly Imprinted Hybrid Materials of Estrogenic Endocrine Disruptors

Abstract

The invention provides the preparation of a molecularly imprinted hybrid material of an estrogenic endocrine disrupter. The preparation comprises the following steps: firstly, loading Fe3O4 microspheres on the surface of graphene by a hydrothermal one-step method to obtain magnetic graphene, and then taking the magnetic graphene as a carrier, and synthesizing a magnetic graphene-based molecularly imprinted nanofilm on the surface of the magnetic graphene through the molecular imprinting technique. The preparation of the molecularly imprinted hybrid material provided by the invention is rational in process and easy to implement; the magnetically functionalized graphene in the prepared magnetic graphene-based molecularly imprinted hybrid material is magnetic and thus convenient to separate, and simultaneously, capable of enhancing the response signals of an electrochemical sensor; the molecularly imprinted hybrid material has the characteristics of excellent chemical stability and reusability, quick response and high sensitivity in detection of estrogen in drinking water; therefore, the molecularly imprinted hybrid material is greatly convenient for the detection of the estrogenic endocrine disrupters; as a result, the utilization efficiency of the molecular imprinting technique can be greatly improved and the range of molecular imprinting application can be expanded.

Description

technical field [0001] The invention relates to the preparation of molecularly imprinted hybrid materials, in particular to the preparation and application of molecularly imprinted hybrid materials of estrogen endocrine disruptors. Background technique [0002] Estrogenic endocrine disruptors are the maintainers of the stability of the endocrine system of female individuals and the maintainers of the second physiological characteristics of female individuals. If estrogen is in an unbalanced state in an individual, it will have adverse effects on the reproductive system, endocrine system and immune system of the organism. It may not only cause deformities of reproductive organs such as testicles and ovaries, but also cause abnormal physiological phenomena such as androgyny and male feminization. As a natural estrogen, estradiol can directly or indirectly affect the nervous system, and then affect the endocrine system. Estrogen enters water bodies through domestic sewage and...

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to overcome the shortcomings of slow response speed, low detection sensitivity and short service life in the traditional detection method of estrogen endocrine disruptors, to provide a preparation of molecularly imprinted hybrid materials of estrogen endocrine disruptors, and to It is applied to the rapid response and high sensitivity detection of estrogen endocrine disruptors in drinking water

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