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Medicament composition for treating diarrhea and preparation method and application thereof

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for treating diarrhea and its preparation and use, and can solve problems such as life-threatening and western medicines having little effect

Inactive Publication Date: 2014-04-23
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, western medicine generally adopts antibacterial treatment and symptomatic treatment for this disease, but it has been verified by many clinical cases that western medicine has basically no effect on malignant and severe diarrhea, resulting in extreme pain for patients, protracted recovery, and even life-threatening

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0024] Take 20g of dried purslane, 18g of Poria cocos skin, 10g of Rhizoma Coptidis, 10g of Scutellaria baicalensis, 10g of Cortex Phellodendron, 12g of Qinpi, 15g of Pulsatilla oleracea, 24g of Pueraria oleracea, 15g of Radix Paeoniae Alba, 12g of Jianqu, 12g of fried hawthorn, 15g of malt (raw, fried Half of each), Guya 15ɡ (raw and fried half), Citrus aurantium 12ɡ, Magnolia officinalis 12ɡ, Raw licorice 8ɡ. Weigh each medicinal herb according to the amount, add water to decoct until boiling, then lower the heat to a simmer, collect the decoction after about 8 to 10 minutes; decoct the medicinal residues with water twice, and combine each decoction to obtain a decoction.

Embodiment 2

[0025] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0026] Take 17g of dried purslane, 16g of Poria cocos skin, 8g of Rhizoma Coptidis, 8g of Scutellaria baicalensis, 8g of Cortex Phellodendron, 10g of Qinpi, 13g of Pulsatilla oleracea, 21g of Pueraria oleracea, 13g of Radix Paeoniae Alba, 10g of Jianqu, 10g of fried hawthorn, 13g of malt (raw, fried Half and half), Guya 13ɡ (raw and fried half), Citrus aurantium 10ɡ, Magnolia officinalis 10ɡ, Raw licorice 6ɡ. First extract twice with 70% v / v ethanol, combine the alcohol extracts, decoct the dregs with water twice, and combine the water decoctions. Concentrate the ethanol extract and water decoction respectively, mix them, add appropriate amount of dextrin and soluble starch, and granulate to obtain granules.

Embodiment 3

[0027] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0028] Take 23g of dried purslane, 20g of Poria cocos skin, 12g of Rhizoma Coptidis, 12g of Scutellaria baicalensis, 12g of Cortex Phellodendron, 14g of Qinpi, 17g of Pulsatilla oleracea, 27g of Pueraria oleracea, 17g of Radix Paeoniae Alba, 14g of Jianqu, 14g of fried hawthorn, 17g of malt (raw and stir-fried). Half and half), Guya 17ɡ (raw and fried half), Citrus aurantium 14ɡ, Magnolia officinalis 14ɡ, Raw licorice 10ɡ. First extract twice with 70% v / v ethanol, combine the alcohol extracts, decoct the dregs with water twice, and combine the water decoctions. Concentrate the alcohol extract and water decoction respectively, mix them, then add appropriate amount of dextrin and soluble starch, granulate and compress into tablets to obtain tablets.

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PUM

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Abstract

The invention provides a medicament composition for treating diarrhea. The medicament composition is a preparation prepared from the following raw materials in parts by weight: 17-23 parts of dried purslane or 55-65 parts of fresh purslane, 16-20 parts of cortex sclerotii poriae, 8-12 parts of coptidis rhizome, 8-12 parts of radix scutellariae, 8-12 parts of cortex phellodendri, 10-14 parts of the bark of ash, 13-17 parts of pulsatilla chinensis regel, 21-27 parts of puerarin, 13-17 parts of radix paeoniae alba, 10-14 parts of medicated leaven, 10-14 parts of hawthorns, 13-17 parts of malts, 13-17 parts of rice sprouts, 10-14 parts of fructus aurantii, 10-14 parts of mangnolia officinalis and 6-10 parts of liquorice. The invention also provides a preparation method and application of the medicament composition. The medicament composition is precision in formula and can effectively treat malignant severe diarrhea which cannot be treated by Western medicines or basically cannot be treated by the Western medicines; a new option is supplied to clinical medicine use.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating diarrhea, a preparation method and application thereof. Background technique [0002] Diarrhea, also known as "diarrhea", refers to increased frequency of bowel movements, loose stools, or watery stools. The ancients called loose stools as "Xie", and those with watery stools as "Xie". The viscera affected by diarrhea are mainly in the spleen, stomach and large and small intestine. The causes of the disease include exogenous evils, improper diet, emotional damage, and weakness of viscera. Spleen deficiency and dampness are the important factors leading to the occurrence of this disease, and the two influence each other and cause each other. Acute diarrhea is due to improper diet, eating raw, cold and unclean things, which damages the spleen and stomach, resulting in abnormal transportation and transformation; The transformation and conduction function is abnormal, so that the clear a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61P1/12
Inventor 李戎杨明王戎儿
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE