Polymer micro-fluidic chip and preparation method thereof

Abstract

The invention discloses a polymer micro-fluidic chip. The polymer micro-fluidic chip comprises a substrate, a cover plate and a liquid storage bath, wherein a micro-channel is formed in the substrate; a groove is formed in the tail end of the micro-channel; a hollow micro-extrusion pipe is arranged in the groove. The invention further discloses a preparation method of the polymer micro-fluidic chip. In the invention provides the novel polymer micro-fluidic chip structure and the preparation method, the micro-extrusion pipe is used, and the micro-extrusion pipe is adopted to replace part of the micro-channel, so that the preparation of the chip can be completed in a partial bonding manner; the bonding difficulty of entire micro-fluidic chip is reduced through the partial bonding; the extruded micro-extrusion pipe is entirely copied, so that the consistency of the cross section of the formed micro-channel is good. The polymer micro-fluidic chip provided by the invention uses the bonding process with the low cost and the high reliability; the bonding difficulty is greatly reduced; the bonding difficulty is improved; the scale and automatic production can be easily realized; the polymer micro-fluidic chip is practical and industrial.

Description

Technical field [0001] The invention relates to a microfluidic chip, in particular to a polymer microfluidic chip and a preparation method thereof. Background technique [0002] Microfluidic chip, also known as micro-analysis system or lab-on-a-chip, is a process of sample preparation, biological and chemical reactions, separation and detection involved in chemistry, biology and other fields, miniaturized or basically reduced to a few It is a technology to detect and analyze the results on a square centimeter chip. Compared with traditional analysis technology, microfluidic chip is a "micro" and "full" analysis technology platform, and it is also the focus of the current development of micro-total analysis system. [0003] In recent years, with the widespread application of polymer materials, some plastics with biochemical compatibility and easy mass production through precision injection molding and hot pressing have become the main materials for manufacturing microfluidic chips ...

AI Technical Summary

Problems solved by technology

[0005] In view of the above problems, the purpose of the present invention is to provide a polymer microfluidic chip that does not require the entire piece of hermetic bonding, and can be prepared by local bonding to obtain a polymer microfluidic chip, which solves the current limitation of polymer microfluidics. The main limiting factors of batch and automated production of fluidic chips

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