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A pharmaceutical composition for treating inflammatory bowel disease, its preparation method and application

A technology for inflammatory bowel disease and composition, which is applied in the field of pharmaceutical compositions and preparations for the treatment of inflammatory bowel disease, can solve the problems of lack of inflammatory bowel disease and the like, and achieves the effects of good curative effect, easy portability and no toxic and side effects

Active Publication Date: 2015-12-09
成都中医大中医药健康产业技术研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, there is currently a lack of drugs that can effectively control inflammatory bowel disease in clinical practice.

Method used

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  • A pharmaceutical composition for treating inflammatory bowel disease, its preparation method and application
  • A pharmaceutical composition for treating inflammatory bowel disease, its preparation method and application
  • A pharmaceutical composition for treating inflammatory bowel disease, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Weigh 100g of Poria cocos polysaccharide, 100g of Atractylodes macrolide, add 200g of starch to granulate, 4g of magnesium stearate, 100g of dextrin, and 100g of microcrystalline cellulose, uniformly prepare granules, and press into tablets to obtain tablets.

Embodiment 2

[0023] Weigh 100g of Poria cocos polysaccharide, 200g of atractylodes lactone, add 300g of starch to granulate, 6g of magnesium stearate, 150g of dextrin, and 150g of microcrystalline cellulose, uniformly prepare granules, and press into tablets to obtain tablets.

Embodiment 3

[0025] Weigh 100 g of polysaccharides from cocos cocos, 300 g of atractylodes macrolide, add 300 g of starch to granulate, 6 g of magnesium stearate, 150 g of dextrin, and 150 g of microcrystalline cellulose, uniformly prepare granules, and compress into tablets to obtain tablets.

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PUM

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Abstract

The invention discloses a medicinal composition for treating inflammatory bowel disease, a preparation method and application thereof. The medicinal composition comprises the following components in parts by weight: 1-10 parts of pachymaran and 1-10 parts of atractylenolide and is an combination of effective components of natural medicinal raw materials or extracts of effective components of medicinal raw materials. Experiments prove that the medicinal composition has a good treatment effect on ulcerative colitis and crohn disease. The medicinal composition can be taken without being decocted, can be prepared into tablets, capsules, pills, granules and oral solutions, is convenient to carry and take; each medicine is non-toxic and harmless before and after component compatibility, and side effects cannot be found after a normal dose is taken. The medicinal composition is clear in component, exact in curative effect and controllable in impurity, and is suitable for industrial production.

Description

technical field [0001] The invention belongs to the technical field of medicines, and relates to a pharmaceutical composition for treating inflammatory bowel disease, in particular to a pharmaceutical composition and a preparation method for treating inflammatory bowel disease which are made from extracts of Chinese herbal decoction pieces as raw materials. Background technique [0002] Inflammatory bowel disease (Inflammatory Boweldisease, IBD) is a group of non-specific chronic gastrointestinal inflammatory diseases, its etiology and pathogenesis have not yet been fully clarified, clinically divided into Crohn's disease (Crohn's disease, CD) and ulcerative colitis (ulcerativecolitis, UC) two types. Crohn's disease is also known as segmental colitis, granulomatous ileitis, or ileocolitis, and its lesions are more common in the terminal ileum and adjacent colon, but all segments of the digestive tract from the mouth to the anus can be involved, showing segmental or jump dis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61P1/00A61P29/00A61P1/04A61K31/365
Inventor 贾波祝捷文跃强刘兴隆李晓红岳美颖
Owner 成都中医大中医药健康产业技术研究院有限公司
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