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Soluble powder of Sargassum polysaccharide for prevention and treatment of colibacillosis in chickens

A technology of sargassum polysaccharides and colibacillosis, which is applied in the direction of antibacterial drugs and powder delivery, and can solve problems such as food safety and unsatisfactory immune effects of bacteria vaccines

Active Publication Date: 2016-03-09
GUANGXI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because there are many serotypes of Escherichia coli, the immune effect of the vaccine is not satisfactory, and drug prevention and treatment is still the main means of controlling the disease
At present, antibiotics and other chemical antibacterial drugs are commonly used in clinical treatment, but the resistance of pathogens is becoming more and more serious, and drug residues also bring food safety problems. As a pure natural extracted drug, the polysaccharide extracted from Chinese herbal medicine has low residue and low drug resistance. No toxic side effects, good control effect and more and more people's attention, it can be used as a key research direction for the prevention and control of livestock and poultry diseases in the future

Method used

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  • Soluble powder of Sargassum polysaccharide for prevention and treatment of colibacillosis in chickens
  • Soluble powder of Sargassum polysaccharide for prevention and treatment of colibacillosis in chickens
  • Soluble powder of Sargassum polysaccharide for prevention and treatment of colibacillosis in chickens

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Preparation of Sargassum polysaccharide

[0011] Weigh the Sargassum powder, add 20 times of distilled water and mix well, soak overnight, heat in 80°C water bath for 8h, extract the solution by centrifuging at 3000r / min for 10min, concentrate the obtained supernatant to 1 / 4 volume with a vacuum rotary evaporator, add 3 Double the volume of 95% ethanol, precipitate overnight, centrifuge at 3000r / min for 10min, discard the supernatant, and vacuum freeze-dry the precipitate to obtain Sargassum polysaccharide.

[0012] Preparation of sargassum polysaccharide soluble powder

[0013] Make the sargassum polysaccharide prepared in step into a solution with a mass concentration of 5% with distilled water, put it in a boiling water bath for 20 minutes; take it out and cool it, centrifuge it at 2000r / min for 10 minutes, and collect the supernatant; according to the mass ratio of 1:20 Add distilled water to the residue after centrifugation, continue to bathe in a boiling water...

Embodiment 2

[0015] Basically the same as in Example 1, except that in step , heat in a water bath at 70°C for 9 hours.

Embodiment 3

[0017] Basically the same as Example 1, only step was heated in a water bath at 90°C for 6 hours.

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Abstract

The invention discloses sargassan soluble powder for preventing and treating chicken colibacillosis, which is prepared from sargassum. Experiments prove that the sargassan soluble powder has the effect of preventing and treating artificially infected chicken colibacillosis; prevention role is played in easy incidence time through specific use, and treatment effect is achieved in incidence of disease. The usage and dosage methods are as follows: the sargassan soluble powder can be taken once per day with water according to 100-400mg per kg body weight, and can be continuously taken for five days. The sargassan soluble powder can be used as a traditional Chinese medicine preparation for preventing and treating chicken colibacillosis, and has the advantages of being purely natural to extract, low in residues, free from toxic and side effects, excellent in prevention and treatment effect, and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine extracts, in particular to a sargassum polysaccharide soluble powder for preventing and treating colibacillosis in chickens. Background technique [0002] Avian colibacillosis is a general term for different types of poultry diseases caused by pathogenic E. coli (E.Coli), including acute sepsis, granuloma, bursitis, perihepatitis, pericarditis, yolk peritonitis, salpingitis, Inflammation, ophthalmitis, arthritis, enteritis and pneumonia, the most common are acute sepsis and yolk peritonitis. In recent years, with the continuous development of my country's intensive chicken industry and the increase in stocking density, the occurrence of colibacillosis is on the rise, especially the morbidity and mortality of chicks are high, and they often die acutely due to sepsis. The poultry industry brings huge economic losses. Because there are many serotypes of Escherichia coli, the imm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/14A61K31/715A61P31/04
Inventor 胡庭俊崔月明韦现色
Owner GUANGXI UNIV