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Process for processing fat-containing fruit seed Chinese herbal medicine ultramicro powder

A technology of ultrafine powder and processing technology, which can be used in medical preparations containing active ingredients, powder delivery, pharmaceutical formulations, etc. The effect of upgrading and promoting the improvement of the manufacturing technology and quality control technology of ultra-fine traditional Chinese medicine decoction pieces

Inactive Publication Date: 2014-06-25
湖南春光九汇现代中药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a new processing technology of oil-containing fruit seed Chinese medicinal material ultrafine powder, which can solve the problems of bonding and particle size when the oil-containing fruit seed Chinese medicinal material is pulverized in the prior art. Failure to meet the requirements, and problems such as excessive heavy metals

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] 1. Research on the selection of crushing auxiliary materials

[0023] Screening suitable crushing excipients not only ensures the superfine pulverization of Chinese herbal medicines such as fruits and seeds containing oil, but also ensures that the excipients used will not pollute the Chinese herbal medicines and affect their medicinal properties. In the end, we chose dextrin as the crushing auxiliary material (crushing aid).

[0024] 2. Research on process conditions and process parameters

[0025] Establish standardized process conditions and parameters, and formulate a series of raw material particle size, auxiliary material dosage, grinding particle size, medium filling rate, crushing temperature, crushing time, degree, etc. Process parameters.

[0026] 3. Process research:

[0027] Firstly, Chinese medicinal materials such as fruits and seeds containing oil are crushed into the coarsest powder of 10-50 mesh, and the coarsest powder of medicinal materials and dex...

Embodiment 2

[0029] According to the method of Example 1, specifically, according to the weight ratio of the coarsest jujube seed powder and dextrin being 1:0.3, it was mixed and pulverized at a temperature of -10 to -20° C. for 120 minutes. Superfine pulverization can reach the effect described in Example 1.

Embodiment 3

[0031] According to the method of Example 1, specifically, the coarsest powder of Arctium Fructus and dextrin were mixed at a weight ratio of 1:0.5, and pulverized at a temperature of -10 to -20° C. for 90 minutes. Superfine pulverization can reach the effect described in Example 1.

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PUM

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Abstract

The invention discloses a process for processing fat-containing fruit seed Chinese herbal medicine ultramicro powder. The process comprises the following steps of firstly crushing a fat-containing fruit seed Chinese herbal medicine into coarsest powder of 10-50 meshes; mixing the medicinal coarsest powder and dextrin according to the weight ratio of the medicinal coarsest powder to the dextrin of (1:0.3)-(1:1); crushing in a low-temperature state at -10-30 DEG C by adopting ultramicro crushing equipment, wherein the medium volume filling rate is 50%-70%, the grain diameter D50 of the powder is less than or equal to 40 micrometers, the grain diameter D90 is less than or equal to 75 micrometers, and the cell wall-breaking ratio is not less than 90%. The process disclosed by the invention can solve the problems that the adhesion and the grain diameter can not meet the requirements, heavy metals exceed the standard, and the like when the fat-containing fruit seed Chinese herbal medicine is crushed in the prior art, and plays a demonstration role in the ultramicro crushing of the fat-containing fruit seed Chinese herbal medicine in the industry.

Description

technical field [0001] The invention belongs to the technical field of preparation of superfine powders of Chinese medicinal materials, and in particular relates to a processing technology of superfine powders of Chinese medicinal materials containing oil and seeds. Background technique [0002] Ultra-micro decoction pieces of traditional Chinese medicine are new types of decoction pieces of traditional Chinese medicine successfully developed by combining ultrafine pulverization technology (cell wall breaking technology), traditional processing technology and modern preparation technology. It can be directly used in formulas without decoction. Ready to use. Supermicro decoction pieces of traditional Chinese medicine not only maintains the characteristics of traditional decoction pieces that can be adapted to syndrome differentiation and treatment, and can be added or subtracted according to the disease, but also overcomes the disadvantages of troublesome decoction and unchan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K47/36A61K36/14A61K36/28A61K36/725A61K36/736A61K36/185
Inventor 蔡光先蔡新亚唐正平丁志平倪忠印周开发胡蓉婉
Owner 湖南春光九汇现代中药有限公司
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