Composition comprising syringaresinol for improving the skin

A technology for improving skin and composition, applied in skin care preparations, skin diseases, drug combinations, etc., can solve the problems of epidermal thickness change, skin aging, connective tissue change, etc., to improve skin wrinkles, prevent melanin production, Excellent anti-aging effect

Inactive Publication Date: 2014-06-25
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, prolonged exposure to UV causes premature aging of the skin, causing wrinkle formation, hyperpigmentation, changes in connective tissue, changes in epidermal thickness, etc.

Method used

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  • Composition comprising syringaresinol for improving the skin
  • Composition comprising syringaresinol for improving the skin
  • Composition comprising syringaresinol for improving the skin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0077] Hereinafter, the present invention will be described in detail by way of examples and test examples. However, the following examples and test examples are for illustrative purposes only, and it is apparent to those of ordinary skill in the art that the scope of the present invention is not limited by the examples and test examples.

[0078] [Example] Separation and analysis of syringaresinol

[0079] 1. Pretreatment of ginseng berries

[0080] Gather fresh ginseng berries. After removing the seeds and peel of the ginseng berry, only the pulp is dried under sunlight or using hot air to obtain dried ginseng berry pulp.

[0081] 2. Isolation and analysis of syringaresinol from ginseng berry pulp extract

[0082] Add 3 L of water or alcohol to 1 kg of dried ginseng berry pulp. After extraction at room temperature or under reflux, it was filtered and concentrated under reduced pressure at 40-45° C. to obtain 300 g of ginseng berry pulp extract. The extract was treated w...

Embodiment 1

[0195] [Formulation Example 1] Lotion

[0196] A lotion was prepared according to the usual method with the following composition.

[0197] 【Table 11】

[0198] Element

Embodiment 2

[0199] [Formulation Example 2] Cream

[0200] A cream was prepared according to the usual method with the following composition.

[0201] 【Table 12】

[0202] Element

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PUM

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Abstract

The present invention relates to a composition for improving the skin, which comprises the compound of chemical formula 1, the derivatives thereof, or the pharmaceutically acceptable salts thereof as active ingredients.

Description

【Technical field】 [0001] The present invention relates to a composition for improving skin, which comprises a compound of Chemical Formula 1, a derivative thereof, or a pharmaceutically acceptable salt thereof as an active ingredient. 【Background technique】 [0002] The color of human skin is determined by various factors, including the activity of melanocytes, which produce melanin, the distribution of blood vessels, the thickness of the skin, the presence of pigments such as carotenoids, bilirubin, and the like. Among them, production of melanin by melanocytes mediated by various enzymes including tyrosinase is one of the most important factors in determining skin color. [0003] Melanin present in the skin plays an important role in protection from UV rays and the like. However, in excess, it is known to induce skin pigmentation such as melasma, freckles, lentigo, accelerate skin aging, and cause skin cancer. [0004] In order to treat or alleviate skin pigmentation cau...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/34A61K8/49A61P17/00A61Q19/00
CPCA61K8/4973A61Q19/00A61K31/34A61K8/9789A61K36/258A61P17/00A61P43/00A61Q19/02A61Q19/08A61Q19/007
Inventor 申贤贞曺始永徐大方朴赞雄金完起李尚骏
Owner AMOREPACIFIC CORP
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