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Intravascular catheter capable of improving surface lubrication and preparation method for same

An inner catheter and blood vessel technology, applied in the field of intravascular catheter and preparation, can solve the problems of high surface friction, platelet adhesion, vascular tissue damage, etc., and achieve the effects of reducing platelet adhesion, reducing thrombosis, and preventing complications.

Inactive Publication Date: 2014-07-02
SHENZHEN SHUNMEI MEDICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, the material of common medical central catheters is mainly polyurethane (TPU). There is a disadvantage of high surface friction, which can easily cause vascular tissue damage and complications, and easily cause platelet adhesion and thrombus formation. At the same time, because the intravascular catheter directly contacts the blood of the human body during use, it is not suitable for antibacterial and anticoagulation. The requirements for the characteristics are also very high

Method used

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  • Intravascular catheter capable of improving surface lubrication and preparation method for same

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Effect test

specific Embodiment 1

[0022] The specific embodiment 1 of the preparation method of the intravascular catheter with improved surface lubrication is:

[0023] Step 1.1 Clean the intravascular catheter of polyurethane material with pure water first, and then fully dry it at room temperature after cleaning;

[0024] Step 1.2 Take out the cleaned intravascular catheter and put it into the vapor deposition chamber. In order to prevent other impurities in the air from affecting the effect of vapor deposition, the vapor deposition chamber is evacuated;

[0025] Step 1.3 Configure parylene active monomer gas:

[0026] Step 1.3.1 first evacuate the deposition gas generation chamber to a vacuum;

[0027] Step 1.3.2 Input the liquid parylene into the deposition gas generation chamber through the feed port;

[0028] Step 1.3.3 and introducing neon gas through the air inlet, or other inert gases, to ensure that the gas carrier used does not chemically react with parylene, which will affect the effect of vapor...

specific Embodiment 2

[0033] In order to further meet the special requirements for anti-infection and anti-coagulation of medical intravascular catheters, the preparation method of the intravascular catheters has been further improved, and specific example 2 is as follows:

[0034] Step 3.1 Clean the intravascular catheter of polyurethane material with pure water first, and then fully dry it at room temperature after cleaning;

[0035] Step 3.2 Add rifampicin, nitrofurazone, and heparin sodium to the soaking agent to make a soaking solution, control the temperature of the soaking solution between 18 and 25 degrees, completely soak the cleaned intravascular catheter in the soaking solution, soak for 10 minutes to 60 minute;

[0036] In step 3.3, the intravascular catheter is taken out, rinsed with pure water, and fully dried, so that a layer of anti-infective agent or anticoagulant is first applied on the intravascular catheter;

[0037] Step 3.4 Take out the cleaned intravascular catheter and put ...

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Abstract

The invention discloses an intravascular catheter capable of improving surface lubrication. The intravascular catheter capable of improving surface lubrication is characterized in that an intravascular catheter made from a polyurethane material is used as a matrix, and a layer of poly-p-xylylene film is coated on the outmost layer. The invention also discloses a preparation method for the intravascular catheter capable of improving surface lubrication simultaneously. The preparation method comprises the following steps: cracking the poly-p-xylylene film into poly-p-xylylene active monomers by using an inert gas as a carrier, then realizing coating for the layer of poly-p-xylylene film on the outmost layer of the intravascular catheter by virtue of a vapour deposition method; because the poly-p-xylylene film rapidly forms a layer of lubrication film with water, the intravascular catheter is excellent in lubrication effect, and the lubrication degree is 10-100 times than that of a common catheter. Therefore, injuries on vascular tissues during catheter insertion are reduced, the occurrence of complications is prevented, the platelet adhesiveness is greatly reduced, and the thrombosis is reduced; the intravascular catheter capable of improving surface lubrication is an upgrade and update product for intravascular catheters.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to an intravascular catheter with antibacterial and anticoagulant properties, especially lubricated surface, and a preparation method. Background technique [0002] At present, the material of common medical central catheters is mainly polyurethane (TPU). There is a disadvantage of high surface friction, which can easily cause vascular tissue damage and complications, and easily cause platelet adhesion and thrombus formation. At the same time, because the intravascular catheter directly contacts the blood of the human body during use, it is not suitable for antibacterial and anticoagulation. The feature requirements are also very high. Contents of the invention [0003] In view of the above defects, the purpose of the present invention is to propose how to reduce the surface friction of the intravascular catheter, while meeting the requirements of antibacterial and anticoagulant. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L29/08A61L29/06A61L29/16
Inventor 王仪平
Owner SHENZHEN SHUNMEI MEDICAL CO LTD
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