A kind of pharmaceutical composition for reducing blood uric acid level and application thereof
A technology of blood uric acid and level, applied in the field of natural medicine, can solve the problem of not finding carboxymethyl tuckahoe polysaccharide to reduce blood uric acid level, etc., and achieve the effects of reducing gout, reducing uric acid, and promoting uric acid excretion
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0015] The preparation of embodiment 1 carboxymethylpachyan (CMP)
[0016] 1) 7.5kg of dried poria cocos was crushed, sieved with an 80-mesh sieve, the poria cocos powder was taken, put into a soaking tank, pumped into 60L of water, stirred evenly, and soaked for 12 hours;
[0017] 2) Prepare 40L of 2.5mol / L sodium hydroxide solution in a glass-lined preparation tank;
[0018] 3) Slowly pump the lye in step 2) into 1), stir evenly, extract for 1.5 hours, press filter, and the filtrate is directly introduced into the glass-lined reaction tank through the pipeline;
[0019] 4) Prepare 50 L of 3.2 mol / L chloroacetic acid solution in a glass-lined neutralization tank;
[0020] 5) Prepare 2.5 mol / L sodium hydroxide solution in a glass-lined preparation tank; cool it, and slowly pump it into step 4) for neutralization reaction, stir evenly, cool down, then pump it into a glass-lined reaction tank, and stir evenly , slowly heating up to 59°C, and reacting at constant temperature fo...
Embodiment 2
[0038] Example 2 Experimental Study of Carboxymethyl Pachyphyllan on Lowering Blood Uric Acid in Rats
[0039] Thirty-four SPF grade healthy male SD rats, weighing 180-220g, were randomly divided into the following three groups according to body weight: normal control group (10 rats), model group (12 rats), and treatment group (12 rats). The normal control group was fed with common feed, and the model control group and treatment group were given high-yeast feed (20% yeast extract + 80% basic feed) + 200 mg / kg potassium oxonate by intragastric administration to prepare hyperuricemia models; While establishing the model, 8 mg / (kg d) of carboxymethylpachyran was injected into the tail vein (administration volume 0.5 ml / 100 g once a day), and the normal control group and the model control group were injected with the same amount of water for injection through the tail vein. . Continuous administration for 6 weeks.
[0040] At the end of the 0th, 2nd, 4th, and 6th weeks of medica...
PUM
Property | Measurement | Unit |
---|---|---|
molecular weight | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com