Naphthyl-based phenazine receptor molecule, test paper and synthesis thereof, and application of receptor molecule in identification of Fe<3+> and H2PO4<->

A technology of H2PO4 and acceptor molecules, applied in the field of ion detection, can solve problems such as water eutrophication

Inactive Publication Date: 2014-08-20
NORTHWEST NORMAL UNIVERSITY
View PDF1 Cites 18 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Dihydrogen phosphate ion and its derivatives play an important role in signal transduction and

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Naphthyl-based phenazine receptor molecule, test paper and synthesis thereof, and application of receptor molecule in identification of Fe&lt;3+&gt; and H2PO4&lt;-&gt;
  • Naphthyl-based phenazine receptor molecule, test paper and synthesis thereof, and application of receptor molecule in identification of Fe&lt;3+&gt; and H2PO4&lt;-&gt;
  • Naphthyl-based phenazine receptor molecule, test paper and synthesis thereof, and application of receptor molecule in identification of Fe&lt;3+&gt; and H2PO4&lt;-&gt;

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0038] The synthesis of acceptor molecules and test paper of the present invention and the continuous recognition of Fe are as follows through specific examples. 3+ and H 2 PO 4 - The application in is further explained.

[0039] 1. Synthesis of receptor molecules: Put 2mmol 2,3-diaminophenazine and 2.2mmol 2-hydroxy-1-naphthaldehyde in a 100 mL round bottom flask, add 20 mL DMF, 1 mL glacial acetic acid, and place in an oil bath Heat to reflux at 80°C for 8h. After the reaction was stopped, cool to room temperature, and a brown precipitate precipitated out, which was filtered and washed three times with hot ethanol solution, and then washed with DMF-H 2O was recrystallized to give a brown powdery product—2-(2-hydroxynaphthyl)- 1 H -imidazo[4,5-b]phenazine G 1 . Yield: 43%.

[0040] G 1 : The melting point is greater than 300°C. m.p. >300℃; 1 H NMR (DMSO- d 6 , 600 MHz) δ 13.11 (s 1H, NH), δ 11.59 (s 1H, OH), δ 8.53 (d 1H ArH), 8.51~8.28 (m 2H, ArH) 8.27~8.09 (m ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a synthesis method of a receptor molecule used for identifying H2PO4<-> and Fe<3+>. The receptor molecule treats a naphthalene ring as a fluorescence signal report group, uses an oxygen atom in a hydroxy group and nitrogen atoms in an imidazolyl group as binding sites of Fe<3+>, and has a strong complexing ability on Fe<3+>, H2PO4<-> and Fe<3+> can form Fe(H2PO4)3 inorganic salt, so Fe<3+> and H2PO4<-> can be continuously fluorescently identified. Results of fluorescence titration experiments show that the receptor has a high detection sensitivity to each of Fe<3+> and H2PO4<->, and the lowest detectable limits reach 0.29ppm and 0.19ppm respectively. The invention also relates to a receptor molecule supported colorimetric test paper. The colorimetric test paper can conveniently and fast fluorescently detect Fe<3+> and H2PO4<->, and has a very good application prospect in the detection fields of Fe<3+> and H2PO4<->.

Description

technical field [0001] The present invention relates to a kind of naphthyl-based phenazine acceptor molecule and its synthetic method; The present invention also relates to this acceptor molecule in continuous recognition Fe 3+ and H 2 PO 4 - The application in the invention belongs to the technical field of ion detection. Background technique [0002] Iron ion Fe 3+ Plays important roles in the human body, such as energy production, oxygen delivery, gene expression, neurotransmission, and enzyme regulation. Iron ions in myosin, hemoglobin, and cytochrome are also one of the important elements. The correct expression of these functions depends on the balance of iron ions in the body. Both iron deficiency and iron excess are harmful to the human body. Examples include Alzheimer's, epilepsy, and Parkinson's disease. Moreover, too much iron ion is also harmful to the environment. Therefore, the research and development of iron ion receptors has received a lot of attent...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07D487/04G01N21/78G01N21/64
CPCC07D487/04C09K11/06C09K2211/1044G01N21/6428G01N21/78G01N2021/6443
Inventor 魏太保高国莹曲文娟史兵兵张有明
Owner NORTHWEST NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap