A Method for Preparation of Ceramic Bone Scaffold by Introducing Continuous Liquid Phase in Selective Laser Sintering

Abstract

When an artificial bone scaffold is manufactured from a biological ceramic powder through selective laser sintering, in order to finish a compacting process in the short time of selective laser sintering, the sintering performance of the biological ceramic material needs improving, therefore a continuous liquid-phase sintering method is provided. Before the biological ceramic powder is sintered, a polymer with bioactivity, biological glass 1393, biological glass 45S5 and akermanite are added according to a certain ratio. For selective laser sintering, the sintering temperature of biological ceramic is usually larger than about 1200 DEG C, in the temperature segment of 300-600 DEG C, the added polymer material such as PLA, PLLA, PLGA and the like with bioactivity is utilized for providing a liquid phase. In the temperature segment of 700-1000 DEG C, the biological glass 1393 is utilized for providing a liquid phase. In the temperature segment of 1100-1200 DEG C, the biological glass 45S5 is utilized for providing a liquid phase. In the temperature segment larger than 1200 DEG C, akermanite is utilized for providing a liquid phase. Therefore, the continuous liquid phase exists in the whole process of selective laser sintering, and the sintering performance of the biological ceramic is improved.

Description

Technical field [0001] The present invention relates to a method for preparing bioceramic bone scaffolds with complex shapes and interconnected porous structures, in particular to a method of using bioactive polymers, bioglass and feldspar to provide continuous liquid phase preparation during selective laser sintering Methods for Bioceramic Bone Scaffolds. Background technique [0002] There are as many as several million patients with fractures and bone defects caused by traffic, sports, disease and natural disasters all over the world every year. In the United States alone, there are 1 million cases of bone repair operations every year, of which 80% need to be implanted with artificial bones. Every year in my country, more than 3 million people suffer from bone defects or missing bones caused by traffic accidents and work-related injuries. Bone transplantation has become the second largest transplant tissue next to blood transfusion, but the research on artificial bone in...

AI Technical Summary

Problems solved by technology

[0005] However, unlike the traditional high-temperature furnace, which takes several hours or even tens of hours for sintering, the selective laser sintering time is only about 0.2-200ms. In such a short period of time, it is almost impossible to achieve solid-state sintering of ceramics. We It is known that the essence of the sintering process is a process of material mass transfer to achieve densification, and the mass transfer rate of the material in the liquid phase is much faster than that in the solid phase. In order to complete the sintering process in a short time of laser selective sintering, There is a need to improve the sintering properties of ceramic materials, so we propose a continuous liquid phase sintering method

Images