Unlock instant, AI-driven research and patent intelligence for your innovation.

Compound pediatric antipyretic suppository and preparation method thereof

A pediatric antipyretic technology, applied in antipyretics, suppository delivery, pharmaceutical formulations, etc., can solve the problems of unstable drug efficacy, difficult quality control, and large irritation, and achieve the promotion of rectal mucosa absorption, fast antipyretic, fast absorption effect

Inactive Publication Date: 2014-11-19
JIANGXI JIUHUA PHARMA
View PDF1 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many kinds of children's antipyretic drugs in the prior art, the formula, quality, and manufacturing process are uneven, the drug effect is unstable, and the quality is difficult to control.
Oral drugs, especially antipyretic and analgesic drugs, are very irritating to the stomach and intestinal tract. When children have symptoms such as fever and infection, the discharge of the contents of the stomach is inhibited. If the drug is difficult to reach the absorption site, the clinical therapeutic effect will also be greatly reduced

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Compound pediatric antipyretic suppository and preparation method thereof
  • Compound pediatric antipyretic suppository and preparation method thereof
  • Compound pediatric antipyretic suppository and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A kind of compound antipyretic suppository for children, each kilogram of this compound antipyretic suppository for children comprises artificial bezoar 5g, Nanbanlangen extract powder 50g, acetaminophen 150g, polysorbate 80 7g and ethylparaben containing 0.105g Ethanol 10g, and the balance is semi-synthetic fatty acid glycerides, wherein the semi-synthetic fatty acid glycerides are glyceryl stearate.

[0020] The preparation method of Nanbanlangen extract powder is as follows: take Nanbanlangen and wash it, add water to decoct twice, combine the decoction, filter, add ethanol after the decoction is concentrated, wherein the volume ratio of ethanol to decoction is 6:4; stir Evenly, stand still, recover ethanol from the filtrate, concentrate, dry, grind into fine powder, and obtain it.

[0021] The concrete preparation steps of this compound children's antipyretic suppository are as follows:

[0022] Add 5g of artificial calculus bezoar, 50g of Nanbanlan root extract po...

Embodiment 2

[0024] A kind of compound antipyretic suppository for children, each kilogram of this compound antipyretic suppository for children comprises artificial bezoar 5g, Nanbanlangen extract powder 50g, acetaminophen 150g, polysorbate 80 7g and ethylparaben containing 0.105g 10 g of ethanol, and the balance is semi-synthetic fatty acid glyceride, wherein the semi-synthetic fatty acid glyceride is glyceryl laurate.

[0025] The preparation method of Nanbanlangen extract powder is as follows: take Nanbanlangen and wash it, add water to decoct twice, combine the decoction, filter, add ethanol after the decoction is concentrated, wherein the volume ratio of ethanol to decoction is 6:4; stir Evenly, stand still, recover ethanol from the filtrate, concentrate, dry, grind into fine powder, and obtain it.

[0026] The concrete preparation steps of this compound children's antipyretic suppository are as follows:

[0027] Add 5g of artificial calculus bezoar, 50g of Nanbanlan root extract po...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a compound pediatric antipyretic suppository. The compound pediatric antipyretic suppository per kg comprises 5g calculus bovis factitius, 50g baphicacanthus root extract powder, 150g acetaminophen, 7g polysorbate 80, 10g alcohol containing 0.105g ethylparaben, and the balance of semisynthetic fatty glyceride. The invention further discloses a preparation method of the compound pediatric antipyretic suppository. The compound pediatric antipyretic suppository is prepared by taking the calculus bovis factitius, the baphicacanthus root extract powder and acetaminophen as a compound together with special auxiliary materials, has the advantages of quick absorption, good curative effect and quick abatement of a fever, and has the good curative effect on pediatric symptoms such as the fever in children, upper respiratory tract infection, bronchitis, palpitation due to fright, swelling and pain in a throat, lung heat, abundant expectoration and cough.

Description

technical field [0001] The invention relates to pharmaceutical preparations, in particular to a compound Xiaoer Tuire suppository and a preparation method thereof. Background technique [0002] Pediatric antipyretic drugs are drugs for the treatment of children with fever such as fever and upper respiratory tract infection. But the kind of children's antipyretic medicine in the prior art is very much at present, and formula, quality, manufacturing process are uneven, and drug effect is unstable, and quality is difficult to control. Oral drugs, especially antipyretic and analgesic drugs, are very irritating to the stomach and intestinal tract. When children have symptoms such as fever and infection, the discharge of the contents of the stomach is inhibited. If the drug is difficult to reach the absorption site, the clinical therapeutic effect will also be greatly reduced. [0003] A compound antipyretic suppository for children with good absorption, good curative effect and...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/195A61K47/34A61K9/02A61P29/00A61P11/00A61P11/04A61P11/10A61P11/14A61K35/413A61K31/167
Inventor 许明景许继石任国权
Owner JIANGXI JIUHUA PHARMA