Nucleotide sequence for coding Bactrian camel cytochrome P450, Bactrian camel cytochrome P450 and application thereof

A technology of nucleotide sequence and cytochrome, applied in the application field of nucleotide sequence, can solve the problems of Bactrian camel's detoxification ability and body temperature regulation, etc.
CN104178501AInactive Publication Date: 2014-12-03XINJIANG WANGYUAN CAMEL MILK IND
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
XINJIANG WANGYUAN CAMEL MILK IND
Publication Date
2014-12-03
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a nucleotide sequence for coding a Bactrian camel cytochrome P450, a Bactrian camel cytochrome P450 and application thereof, relating to the technical field of gene engineering. The main technical scheme is as follows: the nucleotide sequence is 29th-1580th sites in SEQ ID NO:1 in the sequence table; or the nucleotide sequence is hybridized with the 29th-1580th nucleotide sequence in SEQ ID NO:1 in the sequence table under highly strict conditions and used for coding the Bactrian camel cytochrome P450; or the nucleotide sequence has more than 90% of homology with the 29th-1580th nucleotide sequence in SEQ ID NO:1 in the sequence table and used for coding the Bactrian camel cytochrome P450. The Bactrian camel cytochrome P450 is coated by the nucleotide sequence.
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Description

technical field

[0001] The invention relates to the technical field of genetic engineering, in particular to a nucleotide sequence encoding Bactrian camel cytochrome P450, the encoded Bactrian camel cytochrome P450, and the application of the nucleotide sequence. Background technique

[0002] Cytochrome P450 is (cytochromeP450, CYP450) a kind of heme-containing single-chain protein that combines with CO in a reduced state and has an absorption peak at a wavelength of 450nm. It is a superfamily of heme-thiolate proteins. It is mainly found in the microsomes and mitochondria of mammals. It has been found that almost 1000 CYPs are widely distributed in various biological organisms, and about 50 are physiologically functional, which are divided into 17 families and many subfamilies according to the unity of amino acid sequence. It is involved in the metabolism of endogenous substances and exogenous substances including drugs, environmental compounds. In recent years, great pro...

Claims

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